Sugi Predict

Sugi Predict / Compounds / SCHEMBL6166961

SCHEMBL6166961

SCHEMBL6166961

CCN(C)CCN(CC)CC

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.45
▸ ALDH1A1 P00352 1/20 0.45
▸ SIGMAR1 Q99720 1/20 0.39
▸ CA12 O43570 1/20 0.37
▸ CA2 P00918 1/20 0.37
▸ CA3 P07451 1/20 0.37
▸ CA4 P22748 1/20 0.37
▸ CA6 P23280 1/20 0.37
▸ CA5A P35218 1/20 0.37
▸ CA7 P43166 1/20 0.37
▸ CA9 Q16790 1/20 0.37
▸ CA14 Q9ULX7 1/20 0.37
▸ CA5B Q9Y2D0 1/20 0.37
▸ TSHR P16473 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ POLB P06746 1/20 0.32
▸ KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19212955 0.97 KDM4E (0.43) KDM4EALDH1A1SIGMAR1CA12CA2
SCHEMBL14271449 0.97 KDM4E (0.43) KDM4EALDH1A1SIGMAR1CA12CA2
SCHEMBL14271429 0.94 KDM4E (0.42) KDM4EALDH1A1SIGMAR1CA12CA2
SCHEMBL9388290 0.90 CA12 (0.47) KDM4EALDH1A1SIGMAR1CA12CA2
SCHEMBL18643082 0.89 ALDH1A1 (0.39) KDM4EALDH1A1SIGMAR1
SCHEMBL16526089 0.87 CA12 (0.48) KDM4EALDH1A1SIGMAR1CA12CA2
SCHEMBL1948689 0.86 CA12 (0.47) KDM4EALDH1A1CA12CA2CA3
SCHEMBL15219233 0.85 KDM4E (0.36) KDM4EALDH1A1SIGMAR1CA12CA2
SCHEMBL15281187 0.85 KDM4E (0.41) KDM4EALDH1A1SIGMAR1CA12CA2
SCHEMBL14565654 0.82 CA12 (0.53) SIGMAR1CA12CA2CA3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140171431-A1 AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES (CN) 2014-06-19 — — US claimed
EP-2725024-A1 AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) 2014-04-30 — — EP claimed
CN-114725482-B Rechargeable battery and application thereof 江苏环峰电工材料有限公司 2024-09-06 — — CN disclosed
US-11548857-B2 Biodegradable compound, lipid particle, composition comprising lipid particle, and kit KABUSHIKI KAISHA TOSHIBA (JP) 2023-01-10 — — US disclosed
EP-3922267-A1 PEGYLATED RECOMBINANT HUMAN GROWTH HORMONE COMPOUNDS ASCENDIS PHARMA ENDOCRINOLOGY DIVISION A/S (DK) 2021-12-15 — — EP disclosed
WO-2021076886-A1 3-PHENYLSULPHONYL-QUINOLINE DERIVATIVES AS AGENTS FOR TREATING PATHOGENIC BLOOD VESSELS DISORDERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-04-22 — — WO disclosed
EP-3050576-B1 PEGYLATED RECOMBINANT HUMAN GROWTH HORMONE COMPOUNDS ASCENDIS PHARMA ENDOCRINOLOGY DIV A/S (DK) 2021-03-31 — — EP disclosed
EP-3134409-B1 COMPOUNDS AND USE THEREOF IN THE EXPANSION OF HEMATOPOIETIC STEM CELLS AND/OR HEMATOPOIETIC PROGENITOR CELLS UNIV MONTREAL (CA) 2020-02-12 — — EP disclosed
US-10513780-B2 Plating bath composition and method for electroless plating of palladium ATOTECH DEUTSCHLAND GMBH (DE) 2019-12-24 — — US disclosed
EP-3380649-B1 PLATING BATH COMPOSITION AND METHOD FOR ELECTROLESS PLATING OF PALLADIUM ATOTECH DEUTSCHLAND GMBH (DE) 2019-10-30 — — EP disclosed
EP-3380650-B1 PLATING BATH COMPOSITION AND METHOD FOR ELECTROLESS PLATING OF PALLADIUM ATOTECH DEUTSCHLAND GMBH (DE) 2019-10-30 — — EP disclosed
WO-2003020721-A1 PYRROLO PYRIMIDINES AS AGENTS FOR THE INHIBITION OF CYSTEIN PROTEASES NOVARTIS AG (CH) 2003-03-13 — — WO disclosed
US-20020161008-A1 2,4-Substituted pyridine derivatives NEUROGEN CORPORATION 2002-10-31 — — US disclosed
EP-0525997-B1 Catalysts for addition of silicon hydrides to alpha, beta-unsaturated olefinic nitriles DOW CORNING (US) 1996-08-21 — — EP disclosed
EP-0525997-A1 Catalysts for addition of silicon hydrides to alpha, beta-unsaturated olefinic nitriles DOW CORNING CORPORATION (US) 1993-02-03 — — EP disclosed
EP-0520645-A1 Process for preparation of beta-cyanoalkylsilanes DOW CORNING CORPORATION (US) 1992-12-30 — — EP disclosed
US-5126469-A Supported catalysts for addition of silicon hydrides to α,β-unsaturated olefinic nitriles DOW CORNING CORPORATION (US) 1992-06-30 — — US disclosed
US-5126468-A Diamine and copper or copper compound DOW CORNING CORPORATION (US) 1992-06-30 — — US disclosed
US-5103033-A Catalytic reaction of unsaturated nitriles and silicon hydride DOW CORNING CORPORATION (US) 1992-04-07 — — US disclosed
US-4561985-A Hec-bentonite compatible blends UNION CARBIDE CORPORATION (US) 1985-12-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140171431-A1 AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE PLA2G5, LTA4H, PLA2G4A KDM4E 2615/4885ALDH1A1 608/4885SIGMAR1 4568/4885
US-11548857-B2 Biodegradable compound, lipid particle, composition comprising lipid particle, and kit KIT, NPY1R, CCKAR KDM4E 797/4885ALDH1A1 1368/4885SIGMAR1 312/4885
US-20020161008-A1 2,4-Substituted pyridine derivatives GABARAP, GABRB1, GABARAPL1 KDM4E 613/4885ALDH1A1 922/4885SIGMAR1 176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.