SCHEMBL1521980

SCHEMBL1521980

O=C1CCC(=O)OC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4551488 0.87 TRIM24 (0.52)
SCHEMBL6276620 0.82
SCHEMBL1309086 0.73
SCHEMBL120199 0.71
SCHEMBL45244 0.69 TSHR (0.71)
SCHEMBL820078 0.69
SCHEMBL12158591 0.69 TSHR (0.71)
SCHEMBL27402854 0.69
Propiolactone SCHEMBL17977 0.68
SCHEMBL13324558 0.68 TSHR (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4741755-A Certain 4-oxo-3-benzoylvalerolactones and thiolactones STAUFFER CHEMICAL COMPANY (US) 1988-05-03 US claimed
EP-4704910-A1 ANTIBODY-DRUG CONJUGATES FOR DELIVERING CYTOTOXIC AGENTS Biohaven Therapeutics Ltd. (VG) 2026-03-11 EP disclosed
WO-2024226448-A1 ANTIBODY-DRUG CONJUGATES FOR DELIVERING CYTOTOXIC AGENTS BIOHAVEN THERAPEUTICS LTD. (VG) 2024-10-31 WO disclosed
CN-118777178-A Two-step fluorescence labeling flow method for detecting cell surface azide and application thereof 杭州瑞奥生物医药有限公司 2024-10-15 CN disclosed
CN-118603851-A Two-step fluorescence labeling flow method for detecting cell surface azide and application thereof 杭州瑞奥生物医药有限公司 2024-09-06 CN disclosed
US-20230183419-A1 Biodegradable Copolymers and Nanofibrous Scaffold Thereof REGENTS OF THE UNIVERSITY OF MICHIGAN 2023-06-15 US disclosed
US-20220011666-A1 RESIST COMPOSITION, METHOD OF FORMING RESIST PATTERN, COMPOUND, AND RESIN TOKYO OHKA KOGYO CO., LTD. (JP) 2022-01-13 US disclosed
CN-111770754-A Polycyclic derivative regulator, preparation method and application thereof 江苏豪森药业集团有限公司 2020-10-13 CN disclosed
US-10030106-B2 Method and catalyst system for preparing polymers and block copolymers IMPERIAL INNOVATIONS LIMITED (GB) 2018-07-24 US disclosed
US-20180125983-A1 Linear Polyester and Semi-Linear Glycidol Polymer Systems: Formulation and Synthesis of Novel Monomers and Macromolecular Structures UNIV VANDERBILT (US) 2018-05-10 US disclosed
WO-1996021689-A2 BIOLOGICALLY DEGRADABLE POLYMERS, PROCESSES FOR MANUFACTURING THE SAME AND THE USE THEREOF FOR PRODUCING BIODEGRADABLE MOULDED ARTICLES BASF AKTIENGESELLSCHAFT (DE) 1996-07-18 WO disclosed
WO-1996021692-A1 BIOLOGICALLY DEGRADABLE POLYMERS, PROCESS FOR MANUFACTURING THE SAME AND THE USE THEREOF FOR PRODUCING BIODEGRADABLE MOULDED ARTICLES BASF AKTIENGESELLSCHAFT (DE) 1996-07-18 WO disclosed
WO-1996021691-A1 BIOLOGICALLY DEGRADABLE POLYMERS, PROCESSES FOR MANUFACTURING THE SAME AND THE USE THEREOF FOR PRODUCING BIODEGRADABLE MOULDED ARTICLES BASF AKTIENGESELLSCHAFT (DE) 1996-07-18 WO disclosed
WO-1996021690-A1 BIOLOGICALLY DEGRADABLE POLYMERS, PROCESSES FOR MANUFACTURING THE SAME AND THE USE THEREOF FOR PRODUCING BIODEGRADABLE MOULDED ARTICLES BASF AKTIENGESELLSCHAFT (DE) 1996-07-18 WO disclosed
US-4808733-A ENOL ESTER INTERMEDIATE; HERBICIDES STAUFFER CHEMICAL COMPANY (US) 1989-02-28 US disclosed
US-4780124-A HERBICIDES STAUFFER CHEMICAL COMPANY (US) 1988-10-25 US disclosed
US-4780123-A HERBICIDES STAUFFER CHEMICAL COMPANY (US) 1988-10-25 US disclosed
US-4741755-A Certain 4-oxo-3-benzoylvalerolactones and thiolactones STAUFFER CHEMICAL COMPANY (US) 1988-05-03 US disclosed
EP-0249812-A2 Certain 4-oxo-3-benzoylvalerolactones and thiolactones STAUFFER CHEMICAL COMPANY (US) 1987-12-23 EP disclosed
US-4118395-A Method for the production of indolyl lactones FRANTSITS WERNER J 1978-10-03 US disclosed