⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propiolactone SCHEMBL27824600 | 1.00 | TSHR (1.00) | — | |
| Propiolactone SCHEMBL10680620 | 1.00 | — | — | |
| Propiolactone SCHEMBL28387215 | 0.96 | — | — | |
| Propiolactone SCHEMBL31156394 | 0.96 | — | — | |
| Propiolactone SCHEMBL27638447 | 0.96 | — | — | |
| Propiolactone SCHEMBL27551484 | 0.96 | — | — | |
| SCHEMBL13324555 | 0.92 | TSHR (0.85) | — | |
| Cyclopentane SCHEMBL28990854 | 0.92 | ALDH1A1 (0.85) | — | |
| SCHEMBL19638419 | 0.92 | TSHR (0.85) | — | |
| Propiolactone SCHEMBL18277487 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 23758 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260146132-A1 | METHOD FOR INTERFACIAL CHAIN-GROWTH POLYMERIZATION AND ULTRA-HIGH MOLECULAR WEIGHT POLYMER | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) | 2026-05-28 | — | — | US | claimed |
| EP-4747302-A2 | REPAIR AND OPTIMIZATION OF NANOCOMPOSITE MATERIALS | Nanocore ApS (DK) | 2026-05-27 | — | — | EP | claimed |
| US-12637469-B2 | 1H-pyrazole derivative and application thereof as dual target inhibitor of Syk and VEGFR2 | OCUMENSION THERAPEUTICS (SUZHOU) CO., LTD. (CN) | 2026-05-26 | — | — | US | claimed |
| EP-4105216-B1 | DIHYDRONAPHTHYRIDINONE COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | GENFLEET THERAPEUTICS SHANGHAI INC (CN) | 2026-05-20 | — | — | EP | claimed |
| CN-122070479-A | Ultrasonic indicating device and method for monitoring ultrasonic treatment | JP实验室股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-117728005-B | All-solid-state secondary battery and preparation method thereof | 江苏正力新能电池技术股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122030576-A | Walnut essence and preparation method thereof | 杭州盛华香料有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-119684816-B | Fine surface treatment method of zinc halide phthalocyanine | 沈阳化工研究院有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-20260125511-A1 | POLYMERIZATION OF LACTONES IN POLAR PROTIC SOLVENTS | NOVOMER INC (US) | 2026-05-07 | — | — | US | claimed |
| US-20260117021-A1 | POLYPROPIOLACTONES AND METHODS OF PREPARATION USING IONIC LIQUIDS | NOVOMER INC (US) | 2026-04-30 | — | — | US | claimed |
| US-4035389-A | ISOANHYDRIDES, FORMALDEHYDE | EASTMAN KODAK COMPANY (US) | 1977-07-12 | — | — | US | claimed |
| US-4024085-A | Gum removing solution for lithographic plate | FUJI PHOTO FILM CO., LTD. (JA) | 1977-05-17 | — | — | US | claimed |
| US-4018727-A | Chemically convertible tape with in situ synthesized polymer | OWENS-ILLINOIS, INC. (US) | 1977-04-19 | — | — | US | claimed |
| US-3994929-A | Production of 2,2-disubstituted propiolactones | EASTMAN KODAK COMPANY (US) | 1976-11-30 | — | — | US | claimed |
| US-3976623-A | Copolymers of 1,2-dimethoxy-ethylene and β-lactones or cyclic six-membered ring carbonates | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1976-08-24 | — | — | US | claimed |
| US-3957887-A | HEATING 4-HYDROXY-2,4,6-TRIMETHYL-2,5-CYCLOHEXADIENE-1-ONE IN H2O OR METHANOL | TEIJIN LIMITED (JA) | 1976-05-18 | — | — | US | claimed |
| US-3951769-A | Epoxide photopolymerizable compositions containing cyclic amides as gelation inhibitor and methods of polymerizing | AMERICAN CAN COMPANY (US) | 1976-04-20 | — | — | US | claimed |
| US-3950301-A | HYDROXYBENZOTRIAZOLES, FIREPROOFING | GENERAL ELECTRIC COMPANY (US) | 1976-04-13 | — | — | US | claimed |
| US-3950361-A | WITH A SOLID ALKALINE EARTH METAL HYDROXIDE | TEIJIN LTD. (JA) | 1976-04-13 | — | — | US | claimed |
| US-3931237-A | Production of 2,2-disubstituted propiolactones | EASTMAN KODAK COMPANY (US) | 1976-01-06 | — | — | US | claimed |