Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.54 |
| ▸ | MET | P08581 | 2/20 | 0.54 |
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL307479 | 0.88 | MET (0.53) | KDRMETHRH3PROKR1L3MBTL3 | |
| SCHEMBL14839965 | 0.88 | MET (0.53) | KDRMETHRH3PROKR1L3MBTL3 | |
| SCHEMBL307478 | 0.88 | MET (0.53) | KDRMETHRH3PROKR1L3MBTL3 | |
| SCHEMBL15218382 | 0.87 | KDR (0.53) | KDRMETMKNK1HRH3PROKR1 | |
| SCHEMBL10272791 | 0.81 | GRIN3B (0.46) | KDRMETGRIN2DGRIN3BGRIN1 | |
| SCHEMBL14953390 | 0.80 | KDR (0.59) | KDRMETBTKPROKR1FLT1 | |
| SCHEMBL14953388 | 0.80 | KDR (0.59) | KDRMETBTKPROKR1FLT1 | |
| SCHEMBL5242952 | 0.80 | MET (0.49) | KDRMETPROKR1MALT1 | |
| SCHEMBL5242942 | 0.80 | MET (0.49) | KDRMETPROKR1MALT1 | |
| SCHEMBL307027 | 0.78 | KDR (0.71) | KDRMETFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130225581-A1 | NITROGEN-CONTAINING AROMATIC HETEROCYCLIC DERIVATIVE | KYOWA HAKKO KIRIN CO., LTD (JP) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225581-A1 | NITROGEN-CONTAINING AROMATIC HETEROCYCLIC DERIVATIVE | FGFR3, FGFR1, FGFR4 | KDR 48/4885MET 35/4885MKNK1 1357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.