Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860304 | 0.78 | HTR6 (0.49) | HTR6RETSIGMAR1HTR2ALMNA | |
| SCHEMBL5033451 | 0.77 | HTR6 (0.45) | HTR6RETSIGMAR1HTR2ALMNA | |
| SCHEMBL4473077 | 0.77 | HTR6 (0.45) | HTR6RETSIGMAR1HTR2ALMNA | |
| SCHEMBL1539616 | 0.75 | HTR6 (0.53) | HTR6RETSIGMAR1HTR2ALMNA | |
| SCHEMBL29554562 | 0.75 | HTR6 (0.53) | HTR6RETSIGMAR1HTR2ALMNA | |
| SCHEMBL9636599 | 0.75 | HTR6 (0.46) | HTR6RETSIGMAR1HTR2ALMNA | |
| SCHEMBL5031550 | 0.74 | HTR6 (0.43) | HTR6RETSIGMAR1HTR2ALMNA | |
| Hydrochloric Acid SCHEMBL4476293 | 0.74 | HTR6 (0.43) | HTR6RETSIGMAR1HTR2ALMNA | |
| SCHEMBL15224275 | 0.74 | HTR6 (0.38) | HTR6RETSIGMAR1LMNASMN1; SMN2 | |
| SCHEMBL20944811 | 0.73 | HTR6 (0.51) | HTR6RETSIGMAR1HTR2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524846-B1 | Trianionic ligand precursor compounds and uses thereof in constrained geometry catalysts | THE UNIVERSITY OF TOLEDO (US) | 2013-09-03 | — | — | US | disclosed |
| US-8524846-B1 | Trianionic ligand precursor compounds and uses thereof in constrained geometry catalysts | THE UNIVERSITY OF TOLEDO (US) | 2013-09-03 | — | — | US | disclosed |
| US-8524846-B1 | Trianionic ligand precursor compounds and uses thereof in constrained geometry catalysts | THE UNIVERSITY OF TOLEDO (US) | 2013-09-03 | — | — | US | disclosed |