Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15224188 | 0.85 | L3MBTL1 (0.66) | L3MBTL1EPHX2HSD11B1HSD17B10ALDH1A1 | |
| SCHEMBL1923226 | 0.82 | L3MBTL1 (0.61) | L3MBTL1EPHX2HSD11B1HSD17B10ALDH1A1 | |
| SCHEMBL1016262 | 0.80 | L3MBTL1 (0.65) | L3MBTL1EPHX2HSD11B1HSD17B10ALDH1A1 | |
| SCHEMBL19808153 | 0.79 | L3MBTL1 (0.63) | L3MBTL1EPHX2HSD11B1HSD17B10ALDH1A1 | |
| SCHEMBL3114854 | 0.79 | L3MBTL1 (0.57) | L3MBTL1EPHX2HSD11B1HSD17B10SIGMAR1 | |
| SCHEMBL4005434 | 0.78 | L3MBTL1 (0.61) | L3MBTL1EPHX2HSD11B1HSD17B10ALDH1A1 | |
| SCHEMBL4229104 | 0.78 | L3MBTL1 (0.61) | L3MBTL1EPHX2HSD11B1HSD17B10ALDH1A1 | |
| SCHEMBL12968364 | 0.78 | L3MBTL1 (0.72) | L3MBTL1EPHX2HSD11B1HSD17B10ALDH1A1 | |
| SCHEMBL15377775 | 0.78 | L3MBTL1 (0.61) | L3MBTL1EPHX2HSD11B1HSD17B10ALDH1A1 | |
| SCHEMBL13702321 | 0.78 | L3MBTL1 (0.72) | L3MBTL1EPHX2HSD11B1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524894-B2 | Inhibitor compounds of 11-beta-hydroxysteroid dehydrogenase type 1 | LABORATORIOS SALVAT, S.A. (ES) | 2013-09-03 | — | — | US | disclosed |