SCHEMBL15224583

SCHEMBL15224583

CCCCC(C)C(c1ccc(OC#N)cc1)c1ccccc1OC#N

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.33
PTGES O14684 1/20 0.33
ALOX5 P09917 1/20 0.33
PPARG P37231 1/20 0.33
PPARA Q07869 1/20 0.33
SLC2A1 P11166 1/20 0.33
MEN1 O00255 4/20 0.32
KMT2A Q03164 4/20 0.32
OPRM1 P35372 1/20 0.32
OPRD1 P41143 1/20 0.32
GPR88 Q9GZN0 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15225242 0.93 PBRM1 (0.35) PBRM1MEN1KMT2AOPRM1OPRD1
SCHEMBL15224835 0.87 PBRM1 (0.36) PBRM1MEN1KMT2AOPRM1OPRD1
SCHEMBL15224853 0.86 SLC2A1 (0.36) PBRM1SLC2A1GPR88
SCHEMBL15224448 0.84 PBRM1 (0.35) PBRM1MEN1KMT2AOPRM1OPRD1
SCHEMBL15224585 0.84 MEN1 (0.41) PBRM1PTGESALOX5PPARGPPARA
SCHEMBL15224930 0.82 PBRM1 (0.36) PBRM1MEN1KMT2AOPRM1OPRD1
SCHEMBL15224555 0.81 PBRM1 (0.39) PBRM1MEN1KMT2AOPRM1OPRD1
SCHEMBL15224553 0.80 PBRM1 (0.35) PBRM1MEN1KMT2AOPRM1OPRD1
SCHEMBL15224727 0.80 MEN1 (0.40) PPARGSLC2A1MEN1KMT2AOPRM1
SCHEMBL15224547 0.79 MEN1 (0.39) PPARGSLC2A1MEN1KMT2AOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9453126-B2 Cyanate ester compound, curable resin composition containing cyanate ester compound, and cured product thereof MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-09-27 US claimed
US-9453126-B2 Cyanate ester compound, curable resin composition containing cyanate ester compound, and cured product thereof MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-09-27 US disclosed
US-20130281640-A1 CYANATE ESTER COMPOUND, CURABLE RESIN COMPOSITION CONTAINING CYANATE ESTER COMPOUND, AND CURED PRODUCT THEREOF MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-10-24 US disclosed
EP-2634205-A1 CYANATE ESTER COMPOUND, CURABLE RESIN COMPOSITION CONTAINING CYANATE ESTER COMPOUND, AND CURED PRODUCT THEREOF Mitsubishi Gas Chemical Company, Inc. (JP) 2013-09-04 EP disclosed