SCHEMBL15224930

SCHEMBL15224930

CC(C)C(c1ccc(OC#N)cc1)c1ccccc1OC#N

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.36
ALDH1A1 P00352 3/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
AR P10275 1/20 0.33
MEN1 O00255 4/20 0.32
KMT2A Q03164 4/20 0.32
OPRM1 P35372 1/20 0.32
OPRD1 P41143 1/20 0.32
HTR2A P28223 2/20 0.31
SLC6A4 P31645 2/20 0.31
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15224553 0.93 PBRM1 (0.35) PBRM1ALDH1A1SMN1; SMN2ARMEN1
SCHEMBL15224835 0.86 PBRM1 (0.36) PBRM1ALDH1A1SMN1; SMN2ARMEN1
SCHEMBL15224448 0.85 PBRM1 (0.35) PBRM1ALDH1A1SMN1; SMN2ARMEN1
SCHEMBL15225242 0.84 PBRM1 (0.35) PBRM1ALDH1A1SMN1; SMN2ARMEN1
SCHEMBL15224589 0.82 PBRM1 (0.38) PBRM1ALDH1A1GAA
SCHEMBL15224583 0.82 PBRM1 (0.33) PBRM1MEN1KMT2AOPRM1OPRD1
SCHEMBL15224701 0.81 ALDH1A1 (0.33) PBRM1ALDH1A1SMN1; SMN2AR
SCHEMBL15224555 0.80 PBRM1 (0.39) PBRM1MEN1KMT2AOPRM1OPRD1
SCHEMBL15225215 0.79 MEN1 (0.38) PBRM1ALDH1A1SMN1; SMN2ARMEN1
SCHEMBL15224419 0.79 MEN1 (0.39) PBRM1ALDH1A1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9453126-B2 Cyanate ester compound, curable resin composition containing cyanate ester compound, and cured product thereof MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-09-27 US claimed
US-9453126-B2 Cyanate ester compound, curable resin composition containing cyanate ester compound, and cured product thereof MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-09-27 US disclosed
US-20130281640-A1 CYANATE ESTER COMPOUND, CURABLE RESIN COMPOSITION CONTAINING CYANATE ESTER COMPOUND, AND CURED PRODUCT THEREOF MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-10-24 US disclosed
EP-2634205-A1 CYANATE ESTER COMPOUND, CURABLE RESIN COMPOSITION CONTAINING CYANATE ESTER COMPOUND, AND CURED PRODUCT THEREOF Mitsubishi Gas Chemical Company, Inc. (JP) 2013-09-04 EP disclosed