SCHEMBL15224962

SCHEMBL15224962

O=C(O)N(CCCCCCN(CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F)C(=O)O)CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.35
MAPT P10636 1/20 0.35
TSHR P16473 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.30
HTT P42858 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15226121 1.00 USP2 (0.35) USP2MAPTTSHRL3MBTL1HTT
SCHEMBL15224966 1.00 USP2 (0.35) USP2MAPTTSHRL3MBTL1HTT
SCHEMBL15225071 1.00 USP2 (0.35) USP2MAPTTSHRL3MBTL1HTT
SCHEMBL15224867 0.98 USP2 (0.35) USP2MAPTTSHR
SCHEMBL15225088 0.96 USP2 (0.33) USP2MAPTTSHR
SCHEMBL15224936 0.94 KDM4E (0.30) TSHR
SCHEMBL15225051 0.93 FAAH (0.35) USP2MAPTTSHRGAA
SCHEMBL15224856 0.93 FAAH (0.35) USP2MAPTTSHRGAA
SCHEMBL15225246 0.93 USP2 (0.31) USP2MAPTTSHR
SCHEMBL15225053 0.90 CA12 (0.34) USP2MAPTTSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2497082-B1 Fluorurethane as additive in a photopolymer formulation BAYER IP GMBH (DE) 2013-09-04 EP disclosed