Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11973141 | 0.80 | EP300 (0.47) | TSHRMAPTLMNAUSP2CYP3A4 | |
| SCHEMBL11973124 | 0.80 | EP300 (0.47) | TSHRMAPTLMNAUSP2CYP3A4 | |
| SCHEMBL11973121 | 0.80 | EP300 (0.47) | TSHRMAPTLMNAUSP2CYP3A4 | |
| SCHEMBL11973145 | 0.80 | EP300 (0.47) | TSHRMAPTLMNAUSP2CYP3A4 | |
| SCHEMBL11973439 | 0.77 | EP300 (0.43) | TSHRMAPTLMNAUSP2CYP3A4 | |
| SCHEMBL4820549 | 0.77 | — | — | |
| SCHEMBL11973443 | 0.77 | EP300 (0.43) | TSHRMAPTLMNAUSP2CYP3A4 | |
| SCHEMBL383195 | 0.77 | TSHR (0.52) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL7645599 | 0.77 | TSHR (0.52) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL1824796 | 0.77 | TSHR (0.52) | TSHRMAPTABCC4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456255-B1 | PRODUCTION OF OLEFIN POLYMERISATION CATALYSTS | BOREALIS TECH OY (FI) | 2013-09-04 | — | — | EP | disclosed |