Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7641099 | 1.00 | TSHR (0.52) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL383195 | 1.00 | TSHR (0.52) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL7643446 | 1.00 | TSHR (0.52) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL7645599 | 1.00 | TSHR (0.52) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL7642200 | 1.00 | TSHR (0.52) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL3683778 | 0.97 | TSHR (0.50) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL383448 | 0.97 | TSHR (0.48) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL3720954 | 0.95 | TSHR (0.46) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL43730 | 0.92 | — | — | |
| SCHEMBL10456179 | 0.87 | TSHR (0.43) | TSHRALDH1A1ALOX15KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1854804-B1 | Heterocyclic metallocene compounds and use thereof in catalyst systems for producing olefin polymers | BASELL POLYOLEFINE GMBH (DE) | 2011-05-04 | — | — | EP | claimed |
| EP-1392740-B1 | PROCESS FOR THE PREPARATION OF ETHYLENE POLYMERS WITH A BIS-AMIDO TITANIUM COMPOUND | BASELL POLYOLEFINE GMBH (DE) | 2008-08-20 | — | — | EP | claimed |
| EP-1854804-A1 | Heterocyclic metallocene compounds and use thereof in catalyst systems for producing olefin polymers | Basell Polyolefine GmbH (DE) | 2007-11-14 | — | — | EP | claimed |
| US-7112638-B2 | Hetero cyclic metallocene compounds and use thereof in catalyst system for producing olefin polymers | BASELL POLYOLEFINE GMBH (DE) | 2006-09-26 | — | — | US | claimed |
| US-20040097668-A1 | Process for the preparation of ethylene polymers | SANTAN PHARMACEUTICAL CO., LTD. (JP) | 2004-05-20 | — | — | US | claimed |
| EP-1392740-A2 | PROCESS FOR THE PREPARATION OF ETHYLENE POLYMERS WITH A BIS-AMIDO TITANIUM COMPOUND | Basell Polyolefine GmbH (DE) | 2004-03-03 | — | — | EP | claimed |
| US-20030036612-A1 | Hetero cyclic metallocene compounds and use thereof in catalyst system for producing olefin polymers | BASELL POLYOLEFINE GMBH (DE) | 2003-02-20 | — | — | US | claimed |
| WO-2002024769-A2 | PROCESS FOR THE PREPARATION OF ETHYLENE POLYMERS WITH A BIS-AMIDO TITANIUM COMPOUND | BASELL TECHNOLOGY COMPANY B.V. (IT) | 2002-03-28 | — | — | WO | claimed |
| EP-0816399-A1 | Slurry process for the preparation of elastomeric ethylene copolymers | Montell Technology Company bv (NL) | 1998-01-07 | — | — | EP | claimed |
| EP-1648946-B1 | OLEFIN POLYMERIZATION PROCESS | BASELL POLYOLEFINE GMBH (DE) | 2015-07-15 | — | — | EP | disclosed |
| EP-1854804-B1 | Heterocyclic metallocene compounds and use thereof in catalyst systems for producing olefin polymers | BASELL POLYOLEFINE GMBH (DE) | 2011-05-04 | — | — | EP | disclosed |
| EP-1963407-B1 | FILMS COMPRISING DYNAMICALLY VULCANISED THERMOPLASTIC ELASTOMERS | DSM IP ASSETS BV (NL) | 2010-11-10 | — | — | EP | disclosed |
| US-7799722-B2 | Catalyst system for the polymerization of olefin | BASELL POLYOLEFINE GMBH (DE) | 2010-09-21 | — | — | US | disclosed |
| US-7615597-B2 | Process for the copolymerization of ethylene | BASELL POLYOLEFINE GMBH (DE) | 2009-11-10 | — | — | US | disclosed |
| EP-0643078-A2 | Process for the preparation of ethylene polymers and products obtained therefrom | Montell Technology Company bv (NL) | 1995-03-15 | — | — | EP | disclosed |
| EP-0633272-A1 | Supported catalysts for the polymerization of olefins | Montell Technology Company bv (NL) | 1995-01-11 | — | — | EP | disclosed |
| EP-0632066-A1 | Elastomeric copolymers of ethylene with propylene and process for their preparation | Montell Technology Company bv (NL) | 1995-01-04 | — | — | EP | disclosed |
| EP-0624604-A1 | Elastomeric copolymers of ethylene with alpha-olefins and process for their preparation | Montell Technology Company bv (NL) | 1994-11-17 | — | — | EP | disclosed |
| EP-0575875-A2 | Catalysts for the polymerization of olefins | Montell Technology Company bv (NL) | 1993-12-29 | — | — | EP | disclosed |
| WO-1993025591-A1 | PROCESS FOR PREPARING AN ETHYLENIC POLYMER | SPHERILENE S.R.L. (IT) | 1993-12-23 | — | — | WO | disclosed |