Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15225408 | 0.87 | — | — | |
| SCHEMBL15226052 | 0.85 | — | — | |
| SCHEMBL15225755 | 0.85 | AKR1B1 (0.31) | — | |
| SCHEMBL4388631 | 0.81 | TSHR (0.46) | TSHRMAPK1AGTR1LMNACYP1A2 | |
| SCHEMBL15225611 | 0.80 | AGTR1 (0.34) | AGTR1LMNACYP1A2 | |
| SCHEMBL15225719 | 0.80 | AGTR1 (0.34) | AGTR1LMNACYP1A2 | |
| SCHEMBL15225893 | 0.80 | TSHR (0.38) | TSHRMAPK1AGTR1LMNACYP1A2 | |
| SCHEMBL15225363 | 0.79 | AGTR1 (0.34) | TSHRMAPK1AGTR1LMNACYP1A2 | |
| SCHEMBL15225683 | 0.78 | — | — | |
| SCHEMBL15225804 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1642880-B1 | HSP90 FAMILY PROTEIN INHIBITORS | KYOWA HAKKO KIRIN CO LTD (JP) | 2013-09-04 | — | — | EP | claimed |