Cantharidin

Cantharidin

SCHEMBL152261

C[C@@]12C(=O)OC(=O)[C@]1(C)C1CCC2O1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 5/20 1.00
TP53 P04637 5/20 1.00
LMNA P02545 4/20 1.00
SMN1; SMN2 Q16637 4/20 1.00
RAB9A P51151 4/20 1.00
CYP3A4 P08684 3/20 1.00
HIF1A Q16665 3/20 1.00
NPC1 O15118 3/20 1.00
NFKB1 P19838 3/20 1.00
THPO P40225 3/20 1.00
GMNN O75496 3/20 1.00
PMP22 Q01453 3/20 1.00
CYP1A2 P05177 2/20 1.00
MTOR P42345 2/20 1.00
BLM P54132 2/20 1.00
PPM1B O75688 2/20 1.00
PPP1CC P36873 2/20 1.00
TFPI2 P48307 2/20 1.00
PPP5C P53041 2/20 1.00
PPP1CA P62136 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cantharidin SCHEMBL152262 1.00 MAPK1 (1.00) MAPK1TP53LMNASMN1; SMN2RAB9A
Cantharidin SCHEMBL14120808 1.00 MAPK1 (1.00) MAPK1TP53LMNASMN1; SMN2RAB9A
Cantharidin SCHEMBL1805181 1.00 MAPK1 (1.00) MAPK1TP53LMNASMN1; SMN2RAB9A
SCHEMBL20885000 0.84 MAPK1 (0.71) MAPK1TP53LMNASMN1; SMN2RAB9A
SCHEMBL24129015 0.81 MAPK1 (0.67) MAPK1TP53LMNASMN1; SMN2RAB9A
SCHEMBL19619602 0.81 MAPK1 (0.67) MAPK1TP53LMNASMN1; SMN2RAB9A
SCHEMBL20618517 0.78 MAPK1 (0.62) MAPK1TP53LMNASMN1; SMN2RAB9A
SCHEMBL23080410 0.75 TP53 (0.57) MAPK1TP53LMNASMN1; SMN2RAB9A
SCHEMBL3496407 0.74 MAPK1 (0.59) MAPK1TP53LMNASMN1; SMN2RAB9A
SCHEMBL14025795 0.73 MAPK1 (0.57) MAPK1TP53LMNASMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5775 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12635710-B2 Methods of using formaldehyde-free antimicrobial compositions in animal by-product compositions EASTMAN CHEMICAL COMPANY (US) 2026-05-26 US claimed
US-20250332393-A1 DEVICES AND METHODS FOR THE TREATMENT OF BODY SURFACE DISORDERS VERRICA PHARMACEUTICALS INC. (US) 2025-10-30 US claimed
US-20250302794-A1 COMPOSITIONS, METHODS AND SYSTEMS FOR THE TREATMENT OF CUTANEOUS DISORDERS VERRICA PHARMACEUTICALS INC. (US) 2025-10-02 US claimed
US-20250262167-A1 COMPOUNDS, TARGETS AND PATHWAYS FOR MACROPHAGE MODULATION MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2025-08-21 US claimed
US-12343351-B2 Pulmonary function treatment RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2025-07-01 US claimed
WO-2025129271-A1 LIPID DELIVERY VEHICLE THE UNIVERSITY OF QUEENSLAND (AU) 2025-06-26 WO claimed
EP-3966344-B1 KINASE SCREENING ASSAYS UNIV NEWCASTLE (GB) 2025-06-25 EP claimed
WO-2025125890-A1 PROTEIN PHOSPHATASE 2A (PPA2) ANTAGONISTS FOR DENGUE TREATMENT CENTRO DE INVESTIGACIÓN Y DE ESTUDIOS AVANZADOS DEL I.P.N. (MX) 2025-06-19 WO claimed
CN-119950436-A Deep penetration sequential targeting delivery composition and preparation method and application thereof 杭州市西溪医院 2025-05-09 CN claimed
EP-3914286-B1 METHODS OF MITIGATING TOXIC EFFECTS OF VESICANTS AND CAUSTIC GAS JANSSEN PHARMACEUTICA NV (BE) 2025-05-07 EP claimed
CN-1091953-A Cantharidate anti-virus formulation and preparation thereof WANG YUEWEI (CN) 1994-09-14 CN claimed
CN-1076111-A Cantharidate anti-virus formulation and preparation thereof WANG RIWEI (CN) 1993-09-15 CN claimed
CN-1073096-A The preparation of cantharidia liposoluble pharmaceutics WANG RIWEI (CN) 1993-06-16 CN claimed
US-5167649-A Drug delivery system for the removal of dermal lesions ZOOK GERALD P (US) 1992-12-01 US claimed
EP-0506207-A2 Pharmaceutical vehicles for reducing transdermal flux CHEMEX PHARMACEUTICALS, Inc. (US) 1992-09-30 EP claimed
CN-1059338-A The preparation of cantharidia liposoluble pharmaceutics WANG RIWEI (CN) 1992-03-11 CN claimed
CN-2064039-U NON-CAUSING WOUND WOMEN'S PROTECTIVE WEAPON YANG GENYUAN (CN) 1990-10-17 CN claimed
US-4895727-A Using water soluble zinc compound CHEMEX PHARMACEUTICALS, INC. (US) 1990-01-23 US claimed
US-4678664-A POLYETHER BLOCK COPOLYMER BASF CORPORATION (US) 1987-07-07 US claimed
US-4298752-A REMOVAL OF WARTS, APHRODISIAC REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1981-11-03 US claimed