Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.59 |
| ▸ | TP53 | P04637 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | THPO | P40225 | 2/20 | 0.59 |
| ▸ | GMNN | O75496 | 2/20 | 0.59 |
| ▸ | MTOR | P42345 | 2/20 | 0.59 |
| ▸ | BLM | P54132 | 2/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.59 |
| ▸ | PPM1B | O75688 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.59 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.59 |
| ▸ | PPP5C | P53041 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cantharidin SCHEMBL152261 | 0.74 | MAPK1 (1.00) | MAPK1TP53CYP3A4HIF1ALMNA | |
| Cantharidin SCHEMBL152262 | 0.74 | MAPK1 (1.00) | MAPK1TP53CYP3A4HIF1ALMNA | |
| Cantharidin SCHEMBL1805181 | 0.74 | MAPK1 (1.00) | MAPK1TP53CYP3A4HIF1ALMNA | |
| Cantharidin SCHEMBL14120808 | 0.74 | MAPK1 (1.00) | MAPK1TP53CYP3A4HIF1ALMNA | |
| SCHEMBL15384797 | 0.73 | MAPK1 (0.39) | MAPK1TP53CYP3A4HIF1ALMNA | |
| SCHEMBL14025795 | 0.71 | MAPK1 (0.57) | MAPK1TP53CYP3A4HIF1ALMNA | |
| SCHEMBL17663719 | 0.70 | MAPK1 (0.55) | MAPK1TP53CYP3A4HIF1ALMNA | |
| SCHEMBL14025793 | 0.70 | MAPK1 (0.55) | MAPK1TP53CYP3A4HIF1ALMNA | |
| SCHEMBL17663718 | 0.67 | MAPK1 (0.52) | MAPK1TP53CYP3A4HIF1ALMNA | |
| SCHEMBL20885000 | 0.66 | MAPK1 (0.71) | MAPK1TP53CYP3A4HIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137294-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS | GENETIC TECHNOLOGIES LIMITED (AU) | 2010-06-03 | — | — | US | claimed |
| US-8426444-B2 | Oxabicycloheptanes and oxabicycloheptenes, their preparation and use | LIXTE BIOTECHNOLOGY, INC. (US) | 2013-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137294-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS | PPP1R10, TASP1, PPP5C | MAPK1 812/4885TP53 1847/4885CYP3A4 4692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.