Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | F11 | P03951 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31355055 | 0.87 | CA12 (0.48) | CA12CA9F11MAPTAR | |
| SCHEMBL1119897 | 0.87 | CA12 (0.48) | CA12CA9F11MAPTAR | |
| SCHEMBL19376174 | 0.81 | CA12 (0.55) | CA12CA9F11MAPTAR | |
| SCHEMBL30636806 | 0.81 | CA12 (0.55) | CA12CA9F11MAPTAR | |
| SCHEMBL764001 | 0.81 | CA12 (0.59) | CA12CA9F11MAPTAR | |
| SCHEMBL16044071 | 0.81 | F11 (0.59) | CA12CA9F11MAPTAR | |
| SCHEMBL27239601 | 0.81 | CA12 (0.55) | CA12CA9F11MAPTAR | |
| SCHEMBL9269642 | 0.77 | CA12 (0.54) | CA12CA9F11MAPTAR | |
| SCHEMBL21024968 | 0.77 | CA12 (0.54) | CA12CA9F11MAPTAR | |
| SCHEMBL30114885 | 0.77 | CA12 (0.54) | CA12CA9F11MAPTAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337662-A1 | C-LINKED INHIBITORS OF ENL/AF9 YEATS | Bridge Medicines (US) | 2024-03-20 | — | — | EP | disclosed |
| WO-2022240830-A1 | C-LINKED INHIBITORS OF ENL/AF9 YEATS | BRIDGE MEDICINES (US) | 2022-11-17 | — | — | WO | disclosed |
| EP-2819996-A1 | 6 - ALKYNYL PYRIDINES AS SMAC MIMETICS | Boehringer Ingelheim International GmbH (DE) | 2015-01-07 | — | — | EP | disclosed |
| WO-2013127729-A1 | 6 - ALKYNYL PYRIDINES AS SMAC MIMETICS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-09-06 | — | — | WO | disclosed |