Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1523038 | 0.93 | MAPK1 (0.40) | CYP2C9MAPK1HSD17B10NR1I2RXFP1 | |
| SCHEMBL1523427 | 0.88 | CYP2C9 (0.48) | CYP2C9MAPK1HSD17B10NR1I2RXFP1 | |
| SCHEMBL1522557 | 0.88 | MAPK1 (0.50) | CYP2C9MAPK1HSD17B10NR1I2RXFP1 | |
| SCHEMBL7077611 | 0.88 | CYP2C9 (0.59) | CYP2C9MAPK1HSD17B10NR1I2RXFP1 | |
| SCHEMBL1522570 | 0.88 | MAPK1 (0.48) | CYP2C9MAPK1HSD17B10NR1I2RXFP1 | |
| SCHEMBL1522456 | 0.87 | MAPK1 (0.49) | CYP2C9MAPK1HSD17B10NR1I2RXFP1 | |
| SCHEMBL1522826 | 0.87 | MAPK1 (0.49) | CYP2C9MAPK1HSD17B10NR1I2RXFP1 | |
| SCHEMBL1523325 | 0.86 | MAPK1 (0.49) | CYP2C9MAPK1HSD17B10NR1I2RXFP1 | |
| SCHEMBL1522705 | 0.86 | CYP2C9 (0.56) | CYP2C9MAPK1HSD17B10NR1I2RXFP1 | |
| SCHEMBL1522875 | 0.86 | MAPK1 (0.48) | CYP2C9MAPK1HSD17B10NR1I2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361913-A1 | Anti-infective agents | Abbott Laboratories (US) | 2011-08-31 | — | — | EP | disclosed |
| US-7902203-B2 | Anti-infective agents | ABBOTT LABORATORIES, INC. (US) | 2011-03-08 | — | — | US | disclosed |