SCHEMBL15242576

SCHEMBL15242576

C#Cc1ccc(N(c2ccc(-c3ccc(N(c4ccccc4)c4ccccc4)cc3)cc2)c2ccc(-c3ccc(N(c4ccccc4)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
CYP1A2 P05177 2/20 0.45
CYP2C9 P11712 2/20 0.45
MAPT P10636 2/20 0.45
KDM4E B2RXH2 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C19 P33261 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
MEN1 O00255 1/20 0.38
CRHBP P24387 1/20 0.38
KMT2A Q03164 1/20 0.38
ATM Q13315 1/20 0.38
CRHR2 Q13324 1/20 0.38
TLR9 Q9NR96 1/20 0.38
CYP1A1 P04798 1/20 0.38
CYP1B1 Q16678 1/20 0.38
APP P05067 1/20 0.37
KEAP1 Q14145 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12331537 1.00 ALDH1A1 (0.45) ALDH1A1L3MBTL1CYP1A2CYP2C9MAPT
SCHEMBL10160430 0.98 ALDH1A1 (0.43) ALDH1A1L3MBTL1CYP1A2CYP2C9MAPT
SCHEMBL10160387 0.96 CYP1A2 (0.42) ALDH1A1L3MBTL1CYP1A2CYP2C9MAPT
SCHEMBL2433973 0.94 ALDH1A1 (0.50) ALDH1A1L3MBTL1CYP1A2CYP2C9MAPT
SCHEMBL22870228 0.94 ALDH1A1 (0.50) ALDH1A1L3MBTL1CYP1A2CYP2C9MAPT
SCHEMBL20969982 0.94 ALDH1A1 (0.50) ALDH1A1L3MBTL1CYP1A2CYP2C9MAPT
SCHEMBL6279069 0.91 ALDH1A1 (0.38) ALDH1A1L3MBTL1CYP1A2CYP2C9MAPT
SCHEMBL19624742 0.87 CYP1A2 (0.36) ALDH1A1L3MBTL1CYP1A2CYP2C9MAPT
SCHEMBL4570406 0.85 ALDH1A1 (0.39) ALDH1A1L3MBTL1CYP1A2CYP2C9MAPT
SCHEMBL1478591 0.84 HDAC8 (0.43) ALDH1A1L3MBTL1CYP1A2CYP2C9MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2820107-B1 DENDRIMERS CONTAINING LUMINESCENT GOLD(III) COMPOUNDS FOR ORGANIC LIGHT-EMITTING DEVICES AND THEIR PREPARATION UNIV HONG KONG (CN) 2017-11-08 EP disclosed
US-9224962-B2 Dendrimers containing luminescent gold (III) compounds for organic light-emitting devices and their preparation THE UNIVERSITY OF HONG KONG (HK) 2015-12-29 US disclosed
US-9224962-B2 Dendrimers containing luminescent gold (III) compounds for organic light-emitting devices and their preparation THE UNIVERSITY OF HONG KONG (HK) 2015-12-29 US disclosed
US-20130228758-A1 Dendrimers Containing Luminescent Gold (III) Compounds for Organic Light-Emitting Devices and Their Preparation UNIVERSITY OF HONG KONG (CN) 2013-09-05 US disclosed
US-20130228758-A1 Dendrimers Containing Luminescent Gold (III) Compounds for Organic Light-Emitting Devices and Their Preparation UNIVERSITY OF HONG KONG (CN) 2013-09-05 US disclosed