SCHEMBL15259752

SCHEMBL15259752

COc1ccc(C(Nc2ccc3c(c2)C(=O)NC3=O)C(=O)N2CCCC2c2cc(NC(=O)O)ccc2S(=O)(=O)C(C)C)cc1OC

nearest known ligand 0.90

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F7 P08709 20/20 0.90
F3 P13726 20/20 0.90

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15259907 1.00 F7 (0.90) F7F3
SCHEMBL15259751 1.00 F7 (0.90) F7F3
SCHEMBL3093181 0.95 F7 (1.00) F7F3
SCHEMBL3068890 0.95 F7 (1.00) F7F3
SCHEMBL3068885 0.95 F7 (1.00) F7F3
SCHEMBL15259922 0.90 F7 (0.79) F7F3
SCHEMBL15259872 0.90 F7 (0.79) F7F3
SCHEMBL15259765 0.88 F7 (0.90) F7F3
SCHEMBL15259846 0.88 F7 (0.90) F7F3
SCHEMBL15259843 0.86 F7 (0.90) F7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2061756-B1 2-AMINOCARBONYLPHENYLAMINO-2-PHENILACETAMIDES AS FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS BRISTOL MYERS SQUIBB CO (US) 2013-09-25 EP claimed
US-20140357567-A1 METHODS FOR TREATING CANCERS USING ORAL FORMULATIONS OF CYTIDINE ANALOGS CELGENE CORPORATION 2014-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140357567-A1 METHODS FOR TREATING CANCERS USING ORAL FORMULATIONS OF CYTIDINE ANALOGS CDA, DCTD, DCK F7 2652/4885F3 4196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.