Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 13/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 12/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MBTD1 | Q05BQ5 | 5/20 | 0.41 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.41 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15509629 | 0.78 | CHRM2 (0.37) | — | |
| SCHEMBL3626737 | 0.75 | KDM4E (0.38) | L3MBTL1 | |
| SCHEMBL27766995 | 0.72 | NPC1 (0.34) | — | |
| SCHEMBL7320872 | 0.72 | L3MBTL3 (0.45) | L3MBTL3L3MBTL1HRH3MBTD1TP53BP1 | |
| SCHEMBL7581493 | 0.71 | L3MBTL3 (0.48) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL10538464 | 0.70 | L3MBTL3 (0.44) | L3MBTL3L3MBTL1HRH3MBTD1TP53BP1 | |
| SCHEMBL7314532 | 0.70 | L3MBTL3 (0.44) | L3MBTL3L3MBTL1HRH3MBTD1TP53BP1 | |
| SCHEMBL20160890 | 0.67 | L3MBTL3 (0.42) | L3MBTL3L3MBTL1HRH3MBTD1TP53BP1 | |
| SCHEMBL26117153 | 0.67 | L3MBTL3 (0.52) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL26112589 | 0.67 | L3MBTL3 (0.52) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2828253-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | Abide Therapeutics, Inc. (US) | 2015-01-28 | — | — | EP | claimed |
| WO-2013142307-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | ABIDE THERAPEUTICS (US) | 2013-09-26 | — | — | WO | claimed |