SCHEMBL15271663

SCHEMBL15271663

CCCCCCCCCCCSc1ccccn1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.51
KMT2A Q03164 2/20 0.47
MAPT P10636 1/20 0.47
LMNA P02545 3/20 0.46
GPR84 Q9NQS5 1/20 0.46
EHMT2 Q96KQ7 1/20 0.45
EHMT1 Q9H9B1 1/20 0.45
APOBEC3G Q9HC16 1/20 0.45
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
KDM4E B2RXH2 2/20 0.43
USP2 O75604 1/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43
HTT P42858 1/20 0.43
HSP90AA1 P07900 1/20 0.43
SOAT1 P35610 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27959557 1.00 ALDH1A1 (0.51) ALDH1A1KMT2AMAPTLMNAGPR84
SCHEMBL11728517 1.00 ALDH1A1 (0.51) ALDH1A1KMT2AMAPTLMNAGPR84
SCHEMBL10723137 1.00 ALDH1A1 (0.51) ALDH1A1KMT2AMAPTLMNAGPR84
SCHEMBL15271108 1.00 ALDH1A1 (0.51) ALDH1A1KMT2AMAPTLMNAGPR84
SCHEMBL15270973 1.00 ALDH1A1 (0.51) ALDH1A1KMT2AMAPTLMNAGPR84
SCHEMBL15271423 1.00 ALDH1A1 (0.51) ALDH1A1KMT2AMAPTLMNAGPR84
SCHEMBL15270700 1.00 ALDH1A1 (0.51) ALDH1A1KMT2AMAPTLMNAGPR84
SCHEMBL1743693 0.98 ALDH1A1 (0.53) ALDH1A1KMT2AMAPTLMNAGPR84
Ammonia Solution, Strong SCHEMBL1743339 0.96 ALDH1A1 (0.51) ALDH1A1KMT2AMAPTLMNAGPR84
SCHEMBL422519 0.93 ALDH1A1 (0.54) ALDH1A1KMT2AMAPTLMNAEHMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9650456-B2 Process for producing polydienes BRIDGESTONE CORPORATION (JP) 2017-05-16 US disclosed
EP-2825574-B1 PROCESS FOR PRODUCING POLYDIENES BRIDGESTONE CORP (JP) 2016-02-24 EP disclosed
US-20150031845-A1 Process For Producing Polydienes BRIDGESTONE CORPORATION (JP) 2015-01-29 US disclosed
EP-2825574-A1 PROCESS FOR PRODUCING POLYDIENES Bridgestone Corporation (JP) 2015-01-21 EP disclosed
WO-2013138270-A1 PROCESS FOR PRODUCING POLYDIENES BRIDGESTSONE CORPORATION (JP) 2013-09-19 WO disclosed