Sugi Predict

Sugi Predict / Compounds / SCHEMBL1527353

SCHEMBL1527353

SCHEMBL1527353

CCCCCC[C@@H](N)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GRIK1 P39086 2/20 0.69
▸ GRIK2 Q13002 2/20 0.69
▸ SLC1A2 P43004 2/20 0.66
▸ SLC1A1 P43005 2/20 0.66
▸ GSR P00390 1/20 0.61
▸ GPR84 Q9NQS5 3/20 0.59
▸ FFAR1 O14842 1/20 0.59
▸ MAPT P10636 1/20 0.57
▸ LCK P06239 1/20 0.57
▸ PPARD Q03181 1/20 0.57
▸ ZDHHC20 Q5W0Z9 1/20 0.57
▸ ZDHHC2 Q9UIJ5 1/20 0.57
▸ NOD1 Q9Y239 2/20 0.57
▸ SLC1A3 P43003 1/20 0.57
▸ NOS2 P35228 2/20 0.56
▸ DDAH1 O94760 1/20 0.56
▸ ARG2 P78540 4/20 0.55
▸ ARG1 P05089 3/20 0.55
▸ ACE2 Q9BYF1 1/20 0.53
▸ NOS3 P29474 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7889574 1.00 GRIK1 (0.69) GRIK1GRIK2SLC1A2SLC1A1GSR
SCHEMBL7878467 1.00 GRIK1 (0.69) GRIK1GRIK2SLC1A2SLC1A1GSR
SCHEMBL660684 1.00 GRIK1 (0.69) GRIK1GRIK2SLC1A2SLC1A1GSR
SCHEMBL3689310 1.00 GRIK1 (0.69) GRIK1GRIK2SLC1A2SLC1A1GSR
SCHEMBL1738925 1.00 GRIK1 (0.69) GRIK1GRIK2SLC1A2SLC1A1GSR
SCHEMBL23531056 1.00 GRIK1 (0.69) GRIK1GRIK2SLC1A2SLC1A1GSR
SCHEMBL5048329 1.00 GRIK1 (0.69) GRIK1GRIK2SLC1A2SLC1A1GSR
SCHEMBL1960915 1.00 GRIK1 (0.69) GRIK1GRIK2SLC1A2SLC1A1GSR
SCHEMBL7861411 1.00 GRIK1 (0.69) GRIK1GRIK2SLC1A2SLC1A1GSR
SCHEMBL10579474 1.00 GRIK1 (0.69) GRIK1GRIK2SLC1A2SLC1A1GSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4644570-A1 HELICASE MUTANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN HIGH-THROUGHPUT SEQUENCING BGI Shenzhen (CN) 2025-11-05 — — EP claimed
CN-118777613-B Amino acid biomarker of wild and cultured silver carp and application thereof 中国水产科学研究院长江水产研究所 2025-04-15 — — CN claimed
CN-118777613-A Amino acid biomarker of wild and cultured silver carp and application thereof 中国水产科学研究院长江水产研究所 2024-10-15 — — CN claimed
WO-2024138422-A1 PIN DOMAIN, HELICASE CONTAINING SAME, PREPARATION METHOD FOR PIN DOMAIN, AND USE OF PIN DOMAIN 深圳华大生命科学研究院 2024-07-04 — — WO claimed
WO-2024138626-A1 HELICASE TOPIF 1, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN HIGH-THROUGHPUT SEQUENCING 深圳华大生命科学研究院 2024-07-04 — — WO claimed
WO-2024138574-A1 HELICASE AND USE THEREOF 深圳华大生命科学研究院 2024-07-04 — — WO claimed
WO-2024138380-A1 HELICASE, PREPARATION METHOD THEREFOR, AND USE THEREOF IN HIGH-THROUGHPUT SEQUENCING 青岛华大基因研究院 2024-07-04 — — WO claimed
CN-118256603-A Modified enzymes 牛津纳米孔科技公开有限公司 2024-06-28 — — CN claimed
CN-116601297-A Modified helicase and application thereof 北京齐碳科技有限公司 2023-08-15 — — CN claimed
CN-116430047-A Metabolic marker for evaluating colorectal cancer and colorectal cancer risk in progressive stage and application thereof 武汉迈特维尔医学科技有限公司 2023-07-14 — — CN claimed
WO-2022126304-A1 MODIFIED HELICASE AND APPLICATION THEREOF 北京齐碳科技有限公司 2022-06-23 — — WO claimed
CN-114599666-A Pif1-like helicase and application thereof 北京齐碳科技有限公司 2022-06-07 — — CN claimed
EP-1976873-A2 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS Brystol-Myers Squibb Company (US) 2008-10-08 — — EP claimed
US-20070238669-A1 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY 2007-10-11 — — US claimed
WO-2007082264-A2 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY (US) 2007-07-19 — — WO claimed
CN-122029203-A Novel enzymes 牛津纳米孔科技公开有限公司 2026-05-12 — — CN disclosed
US-20260036547-A1 METHODS FOR DETECTING METABOLITES USING A MICROFLUIDIC-BASED CE-MS SYSTEM ASTRAZENECA AB (SE) 2026-02-05 — — US disclosed
EP-1252141-A1 TOSYLPROLINE ANALOGS AS THYMIDYLATE SYNTHASE INHIBITORS Sunesis Pharmaceuticals, Inc. (US) 2002-10-30 — — EP disclosed
WO-2001056987-A1 TOSYLPROLINE ANALOGS AS THYMIDYLATE SYNTHASE INHIBITORS SUNESIS PHARMACEUTICALS, INC. (US) 2001-08-09 — — WO disclosed
US-6143776-A Tosylproline analogs as thymidylate synthase inhibitors SUNESIS PHARMACEUTICALS, INC. (US) 2000-11-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070238669-A1 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES RELATED CONDITIONS GLP1R, GIPR, IAPP GRIK1 1402/4885GRIK2 1764/4885SLC1A2 3742/4885
US-20260036547-A1 METHODS FOR DETECTING METABOLITES USING A MICROFLUIDIC-BASED CE-MS SYSTEM ATP5ME, ATP5MF, ATP5MK GRIK1 2925/4885GRIK2 2207/4885SLC1A2 319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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