Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.69 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.69 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.66 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.66 |
| ▸ | GSR | P00390 | 1/20 | 0.61 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.57 |
| ▸ | PPARD | Q03181 | 1/20 | 0.57 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.57 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.57 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.57 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.57 |
| ▸ | NOS2 | P35228 | 2/20 | 0.56 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.56 |
| ▸ | ARG2 | P78540 | 4/20 | 0.55 |
| ▸ | ARG1 | P05089 | 3/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | NOS3 | P29474 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7889574 | 1.00 | GRIK1 (0.69) | GRIK1GRIK2SLC1A2SLC1A1GSR | |
| SCHEMBL660684 | 1.00 | GRIK1 (0.69) | GRIK1GRIK2SLC1A2SLC1A1GSR | |
| SCHEMBL3689310 | 1.00 | GRIK1 (0.69) | GRIK1GRIK2SLC1A2SLC1A1GSR | |
| SCHEMBL1527353 | 1.00 | GRIK1 (0.69) | GRIK1GRIK2SLC1A2SLC1A1GSR | |
| SCHEMBL1738925 | 1.00 | GRIK1 (0.69) | GRIK1GRIK2SLC1A2SLC1A1GSR | |
| SCHEMBL23531056 | 1.00 | GRIK1 (0.69) | GRIK1GRIK2SLC1A2SLC1A1GSR | |
| SCHEMBL5048329 | 1.00 | GRIK1 (0.69) | GRIK1GRIK2SLC1A2SLC1A1GSR | |
| SCHEMBL1960915 | 1.00 | GRIK1 (0.69) | GRIK1GRIK2SLC1A2SLC1A1GSR | |
| SCHEMBL7861411 | 1.00 | GRIK1 (0.69) | GRIK1GRIK2SLC1A2SLC1A1GSR | |
| SCHEMBL10579474 | 1.00 | GRIK1 (0.69) | GRIK1GRIK2SLC1A2SLC1A1GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8716242-B2 | β-hairpin peptidomimetics | POLYPHOR AG (CH) | 2014-05-06 | — | — | US | disclosed |
| US-20120283196-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2012-11-08 | — | — | US | disclosed |
| US-20120045393-A1 | LHRH-II PEPTIDE ANALOGS | BRACCO IMAGING SPA (IT) | 2012-02-23 | — | — | US | disclosed |
| US-20120045393-A1 | LHRH-II PEPTIDE ANALOGS | BRACCO IMAGING SPA (IT) | 2012-02-23 | — | — | US | disclosed |
| WO-2010107832-A1 | LHRH-II PEPTIDE ANALOGS | BRACCO IMAGING SPA (IT) | 2010-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283196-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | CXCL12, CXCR4, CXCR1 | GRIK1 4195/4885GRIK2 4575/4885SLC1A2 1854/4885 |
| US-20120045393-A1 | LHRH-II PEPTIDE ANALOGS | LHCGR, GNRHR, FSHR | GRIK1 1744/4885GRIK2 1251/4885SLC1A2 2539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.