Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | POLG | P54098 | 2/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.39 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19887010 | 1.00 | POLB (0.46) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL25818685 | 0.88 | POLB (0.48) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL22060524 | 0.87 | POLB (0.45) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL15280907 | 0.84 | POLB (0.49) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL19887009 | 0.84 | POLB (0.47) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL24784384 | 0.84 | POLB (0.49) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL15280801 | 0.84 | POLB (0.47) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL15280768 | 0.84 | POLB (0.49) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL20798787 | 0.83 | POLB (0.58) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL19887005 | 0.82 | ALB (0.35) | ALBPOLGADRB1DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018516-A1 | Agent for Regulating Expression and/or Function of RPS25 Gene | Sumitomo Pharma Co., Ltd. (JP) | 2024-01-18 | — | — | US | disclosed |
| US-20240018516-A1 | Agent for Regulating Expression and/or Function of RPS25 Gene | Sumitomo Pharma Co., Ltd. (JP) | 2024-01-18 | — | — | US | disclosed |
| US-20210207136-A1 | MYOCARDIAL DYSFUNCTION THERAPEUTIC AGENT | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-07-08 | — | — | US | disclosed |
| US-10731159-B2 | Cationic lipid | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-08-04 | — | — | US | disclosed |
| US-9803199-B2 | Cationic lipid | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-10-31 | — | — | US | disclosed |
| US-20160257951-A1 | NOVEL LIPID | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-09-08 | — | — | US | disclosed |
| US-8987226-B2 | Modified single-stranded polynucleotides | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-03-24 | — | — | US | disclosed |
| US-20130253038-A1 | Modified Single-Stranded Polynucleotide | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160257951-A1 | NOVEL LIPID | NPC1L1, CETP, LIPC | POLB 394/4885LMNA 603/4885PDE3A 2565/4885 |
| US-20240018516-A1 | Agent for Regulating Expression and/or Function of RPS25 Gene | RPS25, RPS26, RPS24 | POLB 685/4885LMNA 3557/4885PDE3A 4281/4885 |
| US-10731159-B2 | Cationic lipid | CETP, NPC1L1, LIPA | POLB 404/4885LMNA 467/4885PDE3A 2780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.