Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | HRAS | P01112 | 1/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.38 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15280784 | 1.00 | SLC6A2 (0.50) | SLC6A2LGALS8PDE4DTSHRCYP2C19 | |
| SCHEMBL12585283 | 1.00 | SLC6A2 (0.50) | SLC6A2LGALS8PDE4DTSHRCYP2C19 | |
| SCHEMBL18385936 | 1.00 | SLC6A2 (0.50) | SLC6A2LGALS8PDE4DTSHRCYP2C19 | |
| SCHEMBL14490090 | 0.90 | SLC6A2 (0.54) | SLC6A2LGALS8PDE4DTSHRCYP2C19 | |
| SCHEMBL13775032 | 0.89 | SLC6A2 (0.53) | SLC6A2LGALS8PDE4DTSHRCYP2C19 | |
| SCHEMBL19726103 | 0.89 | SLC6A2 (0.47) | SLC6A2LGALS8PDE4DTSHRCYP2C19 | |
| SCHEMBL19762885 | 0.89 | SLC6A2 (0.44) | SLC6A2LGALS8PDE4DTSHRCYP2C19 | |
| SCHEMBL14413417 | 0.87 | SLC6A2 (0.48) | SLC6A2LGALS8PDE4DTSHRCYP2C19 | |
| SCHEMBL10148639 | 0.87 | SLC6A2 (0.57) | SLC6A2LGALS8PDE4DTSHRCYP2C19 | |
| SCHEMBL19620457 | 0.87 | SLC6A2 (0.48) | SLC6A2LGALS8PDE4DTSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9370529-B2 | Tannin inhibitors of HIV | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2016-06-21 | — | — | US | disclosed |
| US-20160038520-A1 | TANNIN INHIBITORS OF HIV | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2016-02-11 | — | — | US | disclosed |
| US-9181291-B2 | Tannin inhibitors of HIV | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2015-11-10 | — | — | US | disclosed |
| US-20130252909-A1 | TANNIN INHIBITORS OF HIV | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2013-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130252909-A1 | TANNIN INHIBITORS OF HIV | SERPINB1, TSN, FURIN | SLC6A2 3257/4885LGALS8 510/4885PDE4D 3734/4885 |
| US-20160038520-A1 | TANNIN INHIBITORS OF HIV | SERPINB1, TSN, FURIN | SLC6A2 3257/4885LGALS8 510/4885PDE4D 3734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.