SCHEMBL15280813

SCHEMBL15280813

CC(C)(C)C[C@H]1O[C@@H](n2cnc3c(=O)[nH]c(N)nc32)CC1OP(=O)(O)O

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.57
P2RY1 P47900 1/20 0.50
FUT5 Q11128 1/20 0.49
HPRT1 P00492 1/20 0.49
P2RY2 P41231 1/20 0.49
P2RY4 P51582 1/20 0.49
P2RY6 Q15077 1/20 0.49
NT5E P21589 1/20 0.48
TGM2 P21980 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16587303 1.00 POLB (0.57) POLBP2RY1FUT5HPRT1P2RY2
SCHEMBL15280862 0.94 POLB (0.55) POLBP2RY1FUT5HPRT1P2RY2
SCHEMBL24784387 0.92 POLB (0.54) POLBP2RY1FUT5HPRT1P2RY2
SCHEMBL15280795 0.92 POLB (0.54) POLBP2RY1FUT5HPRT1P2RY2
SCHEMBL18057134 0.92 POLB (0.54) POLBP2RY1FUT5HPRT1P2RY2
SCHEMBL24699701 0.92 POLB (0.55) POLBP2RY1FUT5HPRT1P2RY2
SCHEMBL18057132 0.91 POLB (0.52) POLBP2RY1FUT5HPRT1P2RY2
SCHEMBL19887006 0.91 POLB (0.52) POLBP2RY1FUT5HPRT1P2RY2
SCHEMBL16587618 0.90 POLB (0.60) POLBP2RY1FUT5HPRT1P2RY2
SCHEMBL19884490 0.90 POLB (0.60) POLBP2RY1FUT5HPRT1P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8987226-B2 Modified single-stranded polynucleotides DAIICHI SANKYO COMPANY, LIMITED (JP) 2015-03-24 US disclosed
US-20130253038-A1 Modified Single-Stranded Polynucleotide DAIICHI SANKYO COMPANY, LIMITED (JP) 2013-09-26 US disclosed