SCHEMBL24784387

SCHEMBL24784387

CC(C)(C)CC1OC(n2cnc3c(=O)[nH]c(N)nc32)CC1OP(=O)(O)OC(C)(C)C

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.54
FUT5 Q11128 1/20 0.52
P2RY2 P41231 1/20 0.48
P2RY4 P51582 1/20 0.48
P2RY6 Q15077 1/20 0.48
HPRT1 P00492 2/20 0.46
NT5E P21589 1/20 0.45
TGM2 P21980 1/20 0.44
P2RY1 P47900 1/20 0.43
PNP P00491 2/20 0.42
HINT1 P49773 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18057134 1.00 POLB (0.54) POLBFUT5P2RY2P2RY4P2RY6
SCHEMBL15280795 1.00 POLB (0.54) POLBFUT5P2RY2P2RY4P2RY6
SCHEMBL19887006 0.93 POLB (0.52) POLBFUT5P2RY2P2RY4P2RY6
SCHEMBL18057132 0.93 POLB (0.52) POLBFUT5P2RY2P2RY4P2RY6
SCHEMBL15280813 0.92 POLB (0.57) POLBFUT5P2RY2P2RY4P2RY6
SCHEMBL16587303 0.92 POLB (0.57) POLBFUT5P2RY2P2RY4P2RY6
SCHEMBL15280862 0.92 POLB (0.55) POLBFUT5P2RY2P2RY4P2RY6
SCHEMBL24699701 0.91 POLB (0.55) POLBFUT5P2RY2P2RY4P2RY6
SCHEMBL18057119 0.86 POLB (0.51) POLBFUT5P2RY2P2RY4P2RY6
SCHEMBL19887003 0.86 POLB (0.51) POLBFUT5P2RY2P2RY4P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220402963-A1 NUCLEOTIDE PROBES Sony Group Corporation (JP) 2022-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220402963-A1 NUCLEOTIDE PROBES METTL3, SNRPA, L3MBTL3 POLB 22/4885FUT5 3870/4885P2RY2 2336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.