SCHEMBL15280854

SCHEMBL15280854

Cc1cn([C@@H]2O[C@@]3(CC(C)(C)C)CO[C@H]2C3OC(C)(C)C)c(=O)[nH]c1=O

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38
▸ LMNA P02545 1/20 0.37
▸ ALB P02768 1/20 0.37
▸ POLB P06746 1/20 0.37
▸ ADRA1A P35348 1/20 0.37
▸ BLM P54132 1/20 0.37
▸ TYMP P19971 5/20 0.36
▸ TK1 P04183 3/20 0.35
▸ DHFR P00374 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22060534 1.00 ALDH1A1 (0.38) ALDH1A1NPSR1LMNAALBPOLB
SCHEMBL19887045 1.00 ALDH1A1 (0.38) ALDH1A1NPSR1LMNAALBPOLB
SCHEMBL22292264 0.90 ALDH1A1 (0.37) ALDH1A1NPSR1LMNAALBPOLB
SCHEMBL15280852 0.90 ALDH1A1 (0.37) ALDH1A1NPSR1LMNAALBPOLB
SCHEMBL19887039 0.90 ALDH1A1 (0.37) ALDH1A1NPSR1LMNAALBPOLB
SCHEMBL22020946 0.85 ALDH1A1 (0.42) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL19887047 0.85 TYMP (0.40) TYMPTK1
SCHEMBL22292250 0.85 TYMP (0.39) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL19887046 0.85 TYMP (0.39) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL15280889 0.85 TYMP (0.39) ALDH1A1LMNAALBPOLBADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018516-A1 Agent for Regulating Expression and/or Function of RPS25 Gene Sumitomo Pharma Co., Ltd. (JP) 2024-01-18 — — US disclosed
US-8987226-B2 Modified single-stranded polynucleotides DAIICHI SANKYO COMPANY, LIMITED (JP) 2015-03-24 — — US disclosed
US-20130253038-A1 Modified Single-Stranded Polynucleotide DAIICHI SANKYO COMPANY, LIMITED (JP) 2013-09-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018516-A1 Agent for Regulating Expression and/or Function of RPS25 Gene RPS25, RPS26, RPS24 ALDH1A1 4592/4885NPSR1 2123/4885LMNA 3557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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