SCHEMBL15280855

SCHEMBL15280855

COC1[C@@H](OP(=O)(O)OC(C)(C)C)[C@@H](CC(C)(C)C)O[C@H]1n1cnc2c(N)ncnc21

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 1/20 0.55
RNASEL Q05823 7/20 0.54
P2RY1 P47900 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15280847 1.00 ADORA1 (0.55) ADORA1RNASELP2RY1
SCHEMBL22060530 1.00 ADORA1 (0.55) ADORA1RNASELP2RY1
SCHEMBL15280856 0.93 ADORA1 (0.53) ADORA1RNASEL
SCHEMBL19887054 0.93 ADORA1 (0.53) ADORA1RNASEL
SCHEMBL15280780 0.92 ADORA1 (0.51) ADORA1RNASELP2RY1
SCHEMBL22060520 0.92 ADORA1 (0.51) ADORA1RNASELP2RY1
SCHEMBL19887018 0.92 ADORA1 (0.51) ADORA1RNASELP2RY1
SCHEMBL19887071 0.91 RNASEL (0.60) ADORA1RNASELP2RY1
SCHEMBL22292292 0.91 RNASEL (0.60) ADORA1RNASELP2RY1
SCHEMBL15280878 0.91 RNASEL (0.60) ADORA1RNASELP2RY1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180051285-A1 CATIONIC LIPID DAIICHI SANKYO COMPANY, LIMITED (JP) 2018-02-22 US disclosed
US-8987226-B2 Modified single-stranded polynucleotides DAIICHI SANKYO COMPANY, LIMITED (JP) 2015-03-24 US disclosed
US-20130253038-A1 Modified Single-Stranded Polynucleotide DAIICHI SANKYO COMPANY, LIMITED (JP) 2013-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180051285-A1 CATIONIC LIPID CETP, NPC1L1, LIPA ADORA1 986/4885RNASEL 468/4885P2RY1 1529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.