RNASEL — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL432628	0.67	13/20
SCHEMBL427255	0.93	11/20
SCHEMBL375102	0.61	7/20
SCHEMBL682924	0.44	7/20
SCHEMBL599965	0.77	6/20
SCHEMBL195866	0.75	6/20
SCHEMBL479008	0.67	5/20
SCHEMBL263420	0.63	5/20
SCHEMBL263421	0.63	5/20
SCHEMBL216009	0.59	5/20
SCHEMBL625829	0.56	5/20
SCHEMBL675658	0.55	5/20
SCHEMBL33194	0.49	5/20
SCHEMBL278746	0.43	5/20
Allosamidin (SCHEMBL407945)	0.38	5/20
Adenosine Triphosphate (SCHEMBL28356)	0.90	4/20
Adenosine Triphosphate (SCHEMBL28358)	0.90	4/20
Adenosine Triphosphate (SCHEMBL193645)	0.90	4/20
Adenosine Triphosphate (SCHEMBL193647)	0.90	4/20
SCHEMBL668585	0.77	4/20

Clinical trials — most relevant to RNASEL by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Effects of Exercise Training on Systemic Inflammation an Muscle Repair According to the Obstructive Chronic Pulmonary Disease (COPD) Phenotype	PHASE4	UNKNOWN
Long Term Extension Study in Patients With Primary Hyperoxaluria	PHASE3	ACTIVE_NOT_RECRUITING
Clinical Study of EBV-LMP1 Targeted DNAzyme to Treat Nasopharyngeal Carcinoma	PHASE1/PHASE2	COMPLETED
Reverse Transcriptase Inhibitors in AGS	PHASE2	COMPLETED
S0720: Adjuvant Therapy Based on Gene Expression in Stage IA and IB Non-Small Cell Lung Cancer	PHASE2	COMPLETED
Bortezomib, Fluorouracil, and External-Beam Radiation Therapy in Treating Patients With Stage II, Stage III, or Stage IV Rectal Cancer	PHASE1	COMPLETED
Clinical Manifestations and Biomarkers in Amyotrophic Lateral Sclerosis Type 4 and Other Inherited Neurological Disorders of RNA Processing	nan	RECRUITING
The Value of circRNAs (hsa_circ_0004001) in Early Diagnosis of HCC	nan	UNKNOWN
Diagnosis of Inflammatory Bowel Disease	nan	NOT_YET_RECRUITING
Evaluation of a ddPCR Technology for the SARS-CoV-2 Detection in Symptomatic Patients With Suspicion of COVID-19	nan	COMPLETED
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis	nan	COMPLETED
Non-coding RNAs Analysis of Eosinophil Subtypes in Asthma	nan	UNKNOWN
The Role of Circulating CircRNAs and MicroRNAs in Acute Lung Injury	nan	UNKNOWN
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy	nan	UNKNOWN
Liquid Biopsy for Early Detection of Colorectal Cancer Using Circular RNA	nan	RECRUITING
DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study	nan	RECRUITING
X-chromosome Inactivation, Epigenetics and the Transcriptome	nan	COMPLETED
Evaluation of Adenosine Deaminase (ADA) Enzyme Deficiency in Patients With Lymphopenia and/or Elevated Immunoglobulin E	nan	UNKNOWN
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma	nan	COMPLETED
Impact of Weight Loss on the Human Sperm Epitranscriptome	nan	ACTIVE_NOT_RECRUITING
RNA Sequencing in the Framingham Heart Study Third Generation Cohort Exam 2	nan	COMPLETED
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population	nan	COMPLETED
Identification of Novel Bio-markers for Environmental Enteropathy in Children Using an Evidence Based Approach	nan	COMPLETED
Screening of Lysosomal Storage Disorders Diseases in Minority Groups	nan	UNKNOWN
NFC Changes in SLE Patients and Its Correlation With Anti-U1RNPAntibodies and Disease Activity	nan	UNKNOWN
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic	nan	COMPLETED
Genetic Investigation of Cancer Predisposition	nan	NOT_YET_RECRUITING
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia	nan	NOT_YET_RECRUITING
Biomarkers in Patients With Diffuse Large B-Cell Lymphoma Treated With Combination Chemotherapy With or Without Rituximab	nan	COMPLETED
Genetic Analysis in Identifying Late-Occurring Complications in Childhood Cancer Survivors	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a RNASEL binder may also engage these)

Protein	Name	Similarity
Q05921	—	1.000	Q05921 →
Q3UHC2	—	0.991	Q3UHC2 →
Q8TDB6	—	0.990	Q8TDB6 →
Q6GM71	—	0.990	Q6GM71 →
Q5TYM7	—	0.990	Q5TYM7 →
F4IDQ6	—	0.989	F4IDQ6 →
Q38SD2	—	0.989	Q38SD2 →
A7E2S9	—	0.989	A7E2S9 →
Q7KLI1	—	0.989	Q7KLI1 →
B9DHT4	—	0.989	B9DHT4 →
Q9FJ57	—	0.989	Q9FJ57 →
Q6TEQ0	—	0.988	Q6TEQ0 →
Q9TU71	—	0.988	Q9TU71 →
Q9FF09	—	0.988	Q9FF09 →
Q62689	—	0.988	Q62689 →
O65020	—	0.988	O65020 →
D3J163	—	0.988	D3J163 →
Q8BJM7	—	0.988	Q8BJM7 →
Q6C710	—	0.988	Q6C710 →
Q9LX30	—	0.988	Q9LX30 →
Q9FNP4	—	0.987	Q9FNP4 →
O12990	—	0.987	O12990 →
Q2T9W8	—	0.987	Q2T9W8 →
Q8GWG2	—	0.987	Q8GWG2 →
Q6Q4D0	—	0.987	Q6Q4D0 →
D3J162	—	0.987	D3J162 →
Q60462	—	0.987	Q60462 →
O45879	—	0.987	O45879 →
Q6XUX0	—	0.987	Q6XUX0 →
AIPL1	Aryl-hydrocarbon-interacting protein-like 1	0.987	landscape →