Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.87 |
| ▸ | F10 | P00742 | 1/20 | 0.87 |
| ▸ | PRKD3 | O94806 | 8/20 | 0.75 |
| ▸ | PRKCG | P05129 | 8/20 | 0.75 |
| ▸ | PRKCB | P05771 | 8/20 | 0.75 |
| ▸ | PRKCA | P17252 | 8/20 | 0.75 |
| ▸ | PRKCH | P24723 | 8/20 | 0.75 |
| ▸ | PRKCI | P41743 | 8/20 | 0.75 |
| ▸ | PRKCE | Q02156 | 8/20 | 0.75 |
| ▸ | PRKCQ | Q04759 | 8/20 | 0.75 |
| ▸ | PRKCZ | Q05513 | 8/20 | 0.75 |
| ▸ | PRKCD | Q05655 | 8/20 | 0.75 |
| ▸ | PRKD1 | Q15139 | 8/20 | 0.75 |
| ▸ | RAD52 | P43351 | 2/20 | 0.72 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tellimagrandin Ii SCHEMBL29369707 | 0.93 | BACE1 (1.00) | BACE1F10PRKD3PRKCGPRKCB | |
| Eugeniin SCHEMBL618555 | 0.93 | BACE1 (1.00) | BACE1F10PRKD3PRKCGPRKCB | |
| Eugeniin SCHEMBL618554 | 0.93 | BACE1 (1.00) | BACE1F10PRKD3PRKCGPRKCB | |
| SCHEMBL16802809 | 0.90 | BACE1 (0.86) | BACE1F10PRKD3PRKCGPRKCB | |
| SCHEMBL9999979 | 0.90 | BACE1 (0.86) | BACE1F10PRKD3PRKCGPRKCB | |
| SCHEMBL10021533 | 0.90 | BACE1 (0.86) | BACE1F10PRKD3PRKCGPRKCB | |
| Hirtellin A SCHEMBL30515194 | 0.89 | BACE1 (0.91) | BACE1F10PRKD3PRKCGPRKCB | |
| SCHEMBL15280881 | 0.89 | BACE1 (0.80) | BACE1F10PRKD3PRKCGPRKCB | |
| SCHEMBL12824705 | 0.88 | BACE1 (0.85) | BACE1F10PRKD3PRKCGPRKCB | |
| SCHEMBL30385544 | 0.88 | BACE1 (0.85) | BACE1F10PRKD3PRKCGPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9370529-B2 | Tannin inhibitors of HIV | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2016-06-21 | — | — | US | disclosed |
| US-20160038520-A1 | TANNIN INHIBITORS OF HIV | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2016-02-11 | — | — | US | disclosed |
| US-9181291-B2 | Tannin inhibitors of HIV | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2015-11-10 | — | — | US | disclosed |
| US-9181291-B2 | Tannin inhibitors of HIV | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2015-11-10 | — | — | US | disclosed |
| US-20130252909-A1 | TANNIN INHIBITORS OF HIV | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2013-09-26 | — | — | US | disclosed |
| US-20130252909-A1 | TANNIN INHIBITORS OF HIV | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2013-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130252909-A1 | TANNIN INHIBITORS OF HIV | SERPINB1, TSN, FURIN | BACE1 1024/4885F10 861/4885PRKD3 2844/4885 |
| US-20160038520-A1 | TANNIN INHIBITORS OF HIV | SERPINB1, TSN, FURIN | BACE1 1024/4885F10 861/4885PRKD3 2844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.