Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B17 | O75795 | 2/20 | 0.57 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | DRD1 | P21728 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27723139 | 0.85 | UGT2B17 (0.41) | UGT2B17 | |
| SCHEMBL24542980 | 0.85 | UGT2B17 (0.41) | UGT2B17 | |
| SCHEMBL29673089 | 0.85 | UGT2B17 (0.41) | UGT2B17 | |
| SCHEMBL27734788 | 0.79 | UGT2B17 (0.57) | UGT2B17KDM4CSIGMAR1SMN1; SMN2 | |
| SCHEMBL27734724 | 0.76 | ADRA2A (0.40) | UGT2B17SIGMAR1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL27784230 | 0.76 | UGT2B17 (0.32) | UGT2B17 | |
| SCHEMBL5174356 | 0.76 | UGT2B17 (0.53) | UGT2B17KDM4CSIGMAR1KMT2A | |
| SCHEMBL13229169 | 0.75 | KMT2A (0.38) | UGT2B17DRD2DRD1KMT2A | |
| SCHEMBL5272877 | 0.73 | UGT2B17 (0.62) | UGT2B17KDM4CSIGMAR1TAS1R3TAS1R1 | |
| SCHEMBL703510 | 0.73 | UGT2B17 (0.62) | UGT2B17KDM4CSIGMAR1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108467414-B | Material for organic light emitting diode | 通用显示公司 | 2022-09-23 | — | — | CN | disclosed |
| US-9686985-B2 | Fungicide N-cycloalkyl-N-bicyclicmethylene-carboxamide derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-06-27 | — | — | US | disclosed |
| EP-2831048-B1 | FUNGICIDE N-CYCLOALKYL-N-BICYCLICMETHYLENE-CARBOXAMIDE DERIVATIVES | BAYER IP GMBH (DE) | 2017-04-26 | — | — | EP | disclosed |
| US-20160366885-A1 | FUNGICIDE N-CYCLOALKYL-N-BICYCLICMETHYLENE-CARBOXAMIDE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH | 2016-12-22 | — | — | US | disclosed |
| US-9468211-B2 | Fungicide N-cycloalkyl-N-bicyclicmethylene-carboxamide derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-10-18 | — | — | US | disclosed |
| US-20150327548-A1 | FUNGICIDE N-CYCLOALKYL-N-BICYCLICMETHYLENE-CARBOXAMIDE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-11-19 | — | — | US | disclosed |
| EP-2831048-A1 | FUNGICIDE N-CYCLOALKYL-N-BICYCLICMETHYLENE-CARBOXAMIDE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2015-02-04 | — | — | EP | disclosed |
| CN-101855213-B | Therapeutic compounds | ALLERGAN INC | 2014-09-10 | — | — | CN | disclosed |
| WO-2013144086-A1 | FUNGICIDE N-CYCLOALKYL-N-BICYCLICMETHYLENE-CARBOXAMIDE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-10-03 | — | — | WO | disclosed |
| CN-103275058-A | Novel flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | SENOMYX INC | 2013-09-04 | — | — | CN | disclosed |
| CN-101400336-B | Novel flavoring agents, taste modifiers, tastants, taste enhancers, umami or sweeteners and/or enhancers and uses thereof | SENOMYX INC | 2013-06-05 | — | — | CN | disclosed |
| CN-102911213-A | Material for organic light emitting diode | UNIVERSAL DISPLAY CORP | 2013-02-06 | — | — | CN | disclosed |
| CN-101400336-A | Novel flavoring agents, taste modifiers, tastants, taste enhancers, umami or sweeteners and/or enhancers and uses thereof | SENOMYX INC (US) | 2009-04-01 | — | — | CN | disclosed |
| CN-101203142-A | Aromatic amides and ureas and their uses as sweet and/or delicate flavor modifiers, flavouring agents and taste enhancers | SENOMYX INC (US) | 2008-06-18 | — | — | CN | disclosed |
| CN-1308311-C | Novel pyridine- and quinoline-derivatives | HOFFMANN LA ROCHE (CH) | 2007-04-04 | — | — | CN | disclosed |
| CN-1630639-A | novel pyridine-and quinoline-derivatives | HOFFMANN LA ROCHE (CH) | 2005-06-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160366885-A1 | FUNGICIDE N-CYCLOALKYL-N-BICYCLICMETHYLENE-CARBOXAMIDE DERIVATIVES | CBR3, CNPY2, CYP51A1 | UGT2B17 1157/4885KDM4C 362/4885SIGMAR1 3236/4885 |
| US-20150327548-A1 | FUNGICIDE N-CYCLOALKYL-N-BICYCLICMETHYLENE-CARBOXAMIDE DERIVATIVES | CBR3, CNPY2, CYP51A1 | UGT2B17 1157/4885KDM4C 362/4885SIGMAR1 3236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.