Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 6/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15309989 | 0.93 | S1PR1 (0.49) | S1PR1GRIN2BSMN1; SMN2MEN1KMT2A | |
| SCHEMBL15310051 | 0.92 | S1PR1 (0.54) | S1PR1GRIN2BSMN1; SMN2HPGDLMNA | |
| SCHEMBL15310232 | 0.91 | S1PR1 (0.49) | S1PR1GRIN2BSMN1; SMN2MEN1KMT2A | |
| SCHEMBL14797018 | 0.87 | S1PR1 (0.65) | S1PR1GRIN2BSMN1; SMN2LMNACETP | |
| SCHEMBL15309990 | 0.87 | S1PR1 (0.48) | S1PR1GRIN2BSMN1; SMN2MEN1KMT2A | |
| SCHEMBL15310032 | 0.87 | S1PR1 (0.51) | S1PR1GRIN2BSMN1; SMN2RAB9AGAA | |
| SCHEMBL15310001 | 0.85 | S1PR1 (0.53) | S1PR1SMN1; SMN2HPGDLMNAPOLB | |
| SCHEMBL15310087 | 0.83 | S1PR1 (0.63) | S1PR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL15310052 | 0.83 | S1PR1 (0.53) | S1PR1GRIN2BSMN1; SMN2HPGDLMNA | |
| SCHEMBL15310136 | 0.81 | S1PR1 (0.53) | S1PR1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523960-B1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI SA (FR) | 2013-10-16 | — | — | EP | disclosed |