Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15310089 | 0.93 | S1PR1 (0.61) | S1PR1NPC1RAB9AKMT2APOLB | |
| SCHEMBL15310088 | 0.91 | S1PR1 (0.61) | S1PR1NPC1RAB9AKMT2APOLB | |
| SCHEMBL15310091 | 0.87 | S1PR1 (0.59) | S1PR1NPC1RAB9AKMT2APOLB | |
| SCHEMBL14797011 | 0.86 | S1PR1 (0.82) | S1PR1KMT2AMEN1LMNAUSP2 | |
| SCHEMBL15310181 | 0.86 | S1PR1 (0.72) | S1PR1POLBEGFRBTKGAA | |
| SCHEMBL15310051 | 0.86 | S1PR1 (0.54) | S1PR1POLBLMNAALDH1A1CETP | |
| SCHEMBL15310034 | 0.85 | S1PR1 (0.59) | S1PR1NPC1RAB9AKMT2APOLB | |
| SCHEMBL15310010 | 0.84 | S1PR1 (0.74) | S1PR1KMT2APOLBMEN1EGFR | |
| SCHEMBL15310231 | 0.83 | S1PR1 (0.51) | S1PR1NPC1RAB9AKMT2APOLB | |
| SCHEMBL15310217 | 0.83 | S1PR1 (0.59) | S1PR1NPC1RAB9AKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523960-B1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI SA (FR) | 2013-10-16 | — | — | EP | disclosed |