Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 11/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 10/20 | 0.40 |
| ▸ | USP2 | O75604 | 7/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | BTK | Q06187 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 3/20 | 0.38 |
| ▸ | CASP7 | P55210 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15310183 | 0.96 | S1PR1 (0.70) | S1PR1CYP1A2ALDH1A1CYP3A4TSHR | |
| SCHEMBL15310091 | 0.92 | S1PR1 (0.59) | S1PR1ALDH1A1MAPTLMNAPOLB | |
| SCHEMBL15310010 | 0.91 | S1PR1 (0.74) | S1PR1CYP1A2ALDH1A1CYP3A4TSHR | |
| SCHEMBL15310181 | 0.89 | S1PR1 (0.72) | S1PR1CYP1A2ALDH1A1CYP3A4TSHR | |
| SCHEMBL15310194 | 0.88 | S1PR1 (0.71) | S1PR1CYP1A2ALDH1A1CYP3A4TSHR | |
| SCHEMBL15310137 | 0.88 | S1PR1 (0.53) | S1PR1MAPTLMNAPOLBKMT2A | |
| SCHEMBL15309873 | 0.88 | S1PR1 (0.61) | S1PR1CYP1A2ALDH1A1CYP3A4TSHR | |
| SCHEMBL15310158 | 0.87 | S1PR1 (0.53) | S1PR1CYP1A2ALDH1A1CYP3A4TSHR | |
| SCHEMBL15310002 | 0.87 | S1PR1 (0.52) | S1PR1ALDH1A1MAPTLMNAPOLB | |
| SCHEMBL15310088 | 0.85 | S1PR1 (0.61) | S1PR1CYP1A2ALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2470504-B1 | SYNTHESIS OF PROPIVERINE HYDROCHLORIDE | ANDAGAR RAMAKRISHNA RAMESHA (IN) | 2013-10-16 | — | — | EP | disclosed |