Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15310088 | 0.93 | S1PR1 (0.61) | S1PR1POLBLMNAGAALDHA | |
| SCHEMBL15310255 | 0.92 | S1PR1 (0.72) | S1PR1POLBLMNAKMT2AEGFR | |
| SCHEMBL15310089 | 0.91 | S1PR1 (0.61) | S1PR1POLBLMNAGAALDHA | |
| SCHEMBL15310137 | 0.88 | S1PR1 (0.53) | S1PR1POLBLMNAGAANPC1 | |
| SCHEMBL15310183 | 0.88 | S1PR1 (0.70) | S1PR1POLBLMNAEGFRBTK | |
| SCHEMBL15310217 | 0.88 | S1PR1 (0.59) | S1PR1POLBNPC1RAB9AKMT2A | |
| SCHEMBL15310002 | 0.88 | S1PR1 (0.52) | S1PR1POLBLMNAGAATP53 | |
| SCHEMBL15310087 | 0.87 | S1PR1 (0.63) | S1PR1POLBLMNAGAALDHA | |
| SCHEMBL15309990 | 0.84 | S1PR1 (0.48) | S1PR1POLBLMNAGAANPC1 | |
| SCHEMBL15310033 | 0.84 | S1PR1 (0.50) | S1PR1POLBLMNAGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523960-B1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI SA (FR) | 2013-10-16 | — | — | EP | disclosed |