Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 16/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15310300 | 0.92 | HPGD (0.41) | S1PR1S1PR3HPGDFKBP1A | |
| SCHEMBL15310028 | 0.87 | S1PR1 (0.40) | S1PR1S1PR3 | |
| SCHEMBL2227122 | 0.87 | POLB (0.46) | S1PR1HPGDFKBP1A | |
| SCHEMBL2223582 | 0.86 | S1PR1 (0.47) | S1PR1S1PR3 | |
| SCHEMBL15310209 | 0.85 | S1PR1 (0.39) | S1PR1S1PR3 | |
| SCHEMBL15310001 | 0.84 | S1PR1 (0.53) | S1PR1HPGDFKBP1A | |
| SCHEMBL15309861 | 0.82 | POLB (0.42) | HPGDFKBP1A | |
| SCHEMBL15310032 | 0.80 | S1PR1 (0.51) | S1PR1HPGDFKBP1A | |
| SCHEMBL15310136 | 0.79 | S1PR1 (0.53) | S1PR1 | |
| SCHEMBL2227123 | 0.79 | HPGD (0.43) | S1PR1HPGDFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523960-B1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI SA (FR) | 2013-10-16 | — | — | EP | disclosed |