Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 12/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.37 |
| ▸ | ITGAL | P20701 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.37 |
| ▸ | CPT1A | P50416 | 2/20 | 0.37 |
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15309858 | 0.92 | KMT2A (0.42) | S1PR1KMT2ACPT1ACPT2 | |
| SCHEMBL15310209 | 0.91 | S1PR1 (0.39) | S1PR1S1PR3CPT1ACPT2 | |
| SCHEMBL2223287 | 0.90 | KMT2A (0.44) | S1PR1KMT2ACPT1A | |
| SCHEMBL14777954 | 0.90 | KMT2A (0.44) | S1PR1KMT2ACPT1A | |
| SCHEMBL2223315 | 0.88 | GYS1 (0.44) | KMT2ACPT1ACPT2 | |
| SCHEMBL14777269 | 0.88 | GYS1 (0.44) | KMT2ACPT1ACPT2 | |
| SCHEMBL15310299 | 0.87 | S1PR1 (0.47) | S1PR1S1PR3 | |
| SCHEMBL15310300 | 0.85 | HPGD (0.41) | S1PR1S1PR3 | |
| SCHEMBL14777535 | 0.85 | S1PR1 (0.51) | S1PR1KMT2ACPT1ACPT2 | |
| SCHEMBL2224648 | 0.85 | S1PR1 (0.51) | S1PR1KMT2ACPT1ACPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523960-B1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI SA (FR) | 2013-10-16 | — | — | EP | disclosed |