Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | PPARD | Q03181 | 5/20 | 0.38 |
| ▸ | PPARA | Q07869 | 5/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3299440 | 1.00 | TLR8 (0.38) | TLR8TLR7PPARGPPARDPPARA | |
| SCHEMBL3574671 | 0.90 | TLR8 (0.40) | TLR8TLR7PPARGPPARDPPARA | |
| SCHEMBL3574667 | 0.90 | TLR8 (0.40) | TLR8TLR7PPARGPPARDPPARA | |
| SCHEMBL3299890 | 0.85 | TLR8 (0.41) | TLR8TLR7PPARGPPARDPPARA | |
| SCHEMBL3299897 | 0.85 | TLR8 (0.41) | TLR8TLR7PPARGPPARDPPARA | |
| SCHEMBL3308752 | 0.82 | TLR8 (0.42) | TLR8TLR7PPARGPPARDPPARA | |
| SCHEMBL3308747 | 0.82 | TLR8 (0.42) | TLR8TLR7PPARGPPARDPPARA | |
| SCHEMBL15310409 | 0.80 | SIRT2 (0.37) | THRBSLC6A4KDM4ENPSR1MRGPRX4 | |
| SCHEMBL3301977 | 0.80 | SIRT2 (0.37) | THRBSLC6A4KDM4ENPSR1MRGPRX4 | |
| SCHEMBL1455821 | 0.80 | THRB (0.41) | THRBKDM4ENPSR1SMN1; SMN2MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2058317-B1 | AMINOPHOSPHORIC ACID ESTER DERIVATIVE AND S1P RECEPTOR MODULATOR CONTAINING THE SAME AS ACTIVE INGREDIENT | KYORIN SEIYAKU KK (JP) | 2013-10-16 | — | — | EP | disclosed |