Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2945402 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MGLLAKR1C3AKR1C2ASAH2 | |
| SCHEMBL2944802 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MGLLAKR1C3AKR1C2ASAH2 | |
| SCHEMBL2952788 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MGLLAKR1C3AKR1C2ASAH2 | |
| SCHEMBL153579 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MGLLAKR1C3AKR1C2ASAH2 | |
| SCHEMBL154514 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MGLLAKR1C3AKR1C2ASAH2 | |
| SCHEMBL2942292 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MGLLAKR1C3AKR1C2ASAH2 | |
| SCHEMBL6147749 | 0.99 | AKR1C3 (0.47) | ALDH1A1MGLLAKR1C3AKR1C2ASAH2 | |
| Isopropyl Alcohol SCHEMBL28378911 | 0.96 | ASAH2 (0.46) | ALDH1A1MGLLAKR1C3AKR1C2ASAH2 | |
| SCHEMBL1400169 | 0.94 | AKR1C3 (0.48) | ALDH1A1MGLLAKR1C3AKR1C2MAPT | |
| SCHEMBL8669550 | 0.94 | ALDH1A1 (0.45) | ALDH1A1MGLLAKR1C3AKR1C2ASAH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111139229-B | Novel GDSL family lipid hydrolase EII-2 and encoding gene and application thereof | 自然资源部第二海洋研究所 | 2023-05-16 | — | — | CN | claimed |
| CN-111019921-B | High-tolerance lipid hydrolase E93 and encoding gene and application thereof | 自然资源部第二海洋研究所 | 2023-04-28 | — | — | CN | claimed |
| US-8623996-B2 | Cold active enzyme and method thereof | UNIVERSITY PUTRA MALAYSIA (MY) | 2014-01-07 | — | — | US | claimed |
| US-20120058514-A1 | COLD ACTIVE ENZYME AND METHOD THEREOF | UNIVERSITY PUTRA MALAYSIA (MY) | 2012-03-08 | — | — | US | claimed |
| CN-118272342-A | Lipase LUCA based on ancestral sequence reconstruction and application thereof | 山东师范大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-116814589-A | Thermokalite-stable ester bond hydrolase and application of mixed enzyme preparation containing same in degradation of PET (polyethylene terephthalate) products | 南京师范大学 | 2023-09-29 | — | — | CN | disclosed |
| CN-112430610-B | Low-temperature esterase functional gene DcaE and application thereof | 中国农业科学院生物技术研究所 | 2023-06-27 | — | — | CN | disclosed |
| CN-111139229-B | Novel GDSL family lipid hydrolase EII-2 and encoding gene and application thereof | 自然资源部第二海洋研究所 | 2023-05-16 | — | — | CN | disclosed |
| CN-111019921-B | High-tolerance lipid hydrolase E93 and encoding gene and application thereof | 自然资源部第二海洋研究所 | 2023-04-28 | — | — | CN | disclosed |
| CN-111057691-B | Novel GDSL family lipid hydrolase EII-3 and encoding gene and application thereof | 自然资源部第二海洋研究所 | 2023-04-28 | — | — | CN | disclosed |
| CN-115975983-A | Application of alkali-resistant broad-spectrum plastic degrading enzyme | 北京理工大学 | 2023-04-18 | — | — | CN | disclosed |
| CN-115838704-A | Lipase mutant and application thereof | 中国海洋大学 | 2023-03-24 | — | — | CN | disclosed |
| EP-0233656-B1 | MICROBIAL ESTERASE AND PROCESS FOR THE PREPARATION OF 2-ARYLPROPIONIC ACIDS | GIST-BROCADES N.V. (NL) | 1992-07-08 | — | — | EP | disclosed |
| EP-0191217-B2 | PROCESS FOR PRODUCING GLYCERIDES IN THE PRESENCE OF LIPASES | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1992-02-19 | — | — | EP | disclosed |
| WO-1991003563-A1 | METHOD OF PREPARATION OF MONOGLYCERIDES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1991-03-21 | — | — | WO | disclosed |
| US-4933287-A | FROM PSEUDOMONAS PSEUDOALCALIGENES OR STUTZERI | GIST-BROCADES N.V. (NL) | 1990-06-12 | — | — | US | disclosed |
| EP-0191217-B1 | PROCESS FOR PRODUCING GLYCERIDES IN THE PRESENCE OF LIPASES | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1988-03-16 | — | — | EP | disclosed |
| WO-1987000859-A1 | NOVEL LIPOLYTIC ENZYMES AND THEIR USE IN DETERGENT COMPOSITIONS | GIST-BROCADES N.V. (NL) | 1987-02-12 | — | — | WO | disclosed |
| EP-0191217-A1 | Process for producing glycerides in the presence of lipases | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1986-08-20 | — | — | EP | disclosed |
| US-4097665-A | Diacylnucleosides and process for preparing the same | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) | 1978-06-27 | — | — | US | disclosed |