Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.67 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.67 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.67 |
| ▸ | GRIK1 | P39086 | 15/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 14/20 | 0.50 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15238580 | 1.00 | SLC1A3 (0.67) | SLC1A3SLC1A2SLC1A1GRIK1GRIK2 | |
| SCHEMBL3360096 | 0.85 | SLC7A5 (0.62) | SLC7A5 | |
| SCHEMBL3360097 | 0.85 | SLC7A5 (0.62) | SLC7A5 | |
| SCHEMBL13725557 | 0.81 | SLC1A1 (0.75) | SLC1A3SLC1A2SLC1A1GRIK1GRM2 | |
| SCHEMBL1819024 | 0.81 | SLC1A1 (0.75) | SLC1A3SLC1A2SLC1A1GRIK1GRM2 | |
| SCHEMBL13725911 | 0.81 | SLC1A1 (0.75) | SLC1A3SLC1A2SLC1A1GRIK1GRM2 | |
| SCHEMBL133913 | 0.80 | SLC1A1 (1.00) | SLC1A3SLC1A2SLC1A1GRIK1GRM2 | |
| SCHEMBL2265548 | 0.80 | SLC1A1 (1.00) | SLC1A3SLC1A2SLC1A1GRIK1GRM2 | |
| SCHEMBL130817 | 0.80 | SLC1A1 (1.00) | SLC1A3SLC1A2SLC1A1GRIK1GRM2 | |
| SCHEMBL8377822 | 0.80 | SLC1A1 (1.00) | SLC1A3SLC1A2SLC1A1GRIK1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2646048-B1 | STABLE HELICAL IONIC POLYPEPTIDES | UNIV ILLINOIS (US) | 2017-11-01 | — | — | EP | disclosed |
| US-9243040-B2 | Stable helical ionic polypeptides | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-01-26 | — | — | US | disclosed |
| US-20150057433-A1 | PREPARATION OF FUNCTIONALIZED POLYPEPTIDES, PEPTIDES, AND PROTEINS BY ALKYLATION OF THIOETHER GROUPS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-02-26 | — | — | US | disclosed |
| US-20130274173-A1 | STABLE HELICAL IONIC POLYPEPTIDES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150057433-A1 | PREPARATION OF FUNCTIONALIZED POLYPEPTIDES, PEPTIDES, AND PROTEINS BY ALKYLATION OF THIOETHER GROUPS | PTMS, TMT1A, PTMA | SLC1A3 1013/4885SLC1A2 1639/4885SLC1A1 1251/4885 |
| US-20130274173-A1 | STABLE HELICAL IONIC POLYPEPTIDES | GHITM, SLC7A1, PICALM | SLC1A3 86/4885SLC1A2 187/4885SLC1A1 73/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.