SCHEMBL15312290

SCHEMBL15312290

CCOc1c(C(=O)O)ccc(CC)c1CC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.40
TSHR P16473 3/20 0.40
METAP2 P50579 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
MEN1 O00255 2/20 0.38
RAB9A P51151 2/20 0.38
KMT2A Q03164 2/20 0.38
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 3/20 0.38
HPGD P15428 3/20 0.38
LMNA P02545 2/20 0.38
MAPT P10636 2/20 0.38
ABL1 P00519 1/20 0.38
GAA P10253 1/20 0.38
RIN1 Q13671 1/20 0.38
MRGPRX4 Q96LA9 1/20 0.37
GABRP O00591 2/20 0.37
GABRD O14764 2/20 0.37
GABRA1 P14867 2/20 0.37
GABRB1 P18505 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31068664 0.89 HSD17B10 (0.42) HSD17B10TSHRMETAP2SMN1; SMN2MEN1
SCHEMBL6712302 0.87 POLB (0.36) HSD17B10TSHRMETAP2SMN1; SMN2MEN1
SCHEMBL5159925 0.85 HSD17B10 (0.39) HSD17B10TSHRSMN1; SMN2MEN1RAB9A
SCHEMBL17560293 0.83 HSD17B10 (0.49) HSD17B10TSHRSMN1; SMN2MEN1RAB9A
SCHEMBL27858196 0.83 TSHR (0.48) HSD17B10TSHRSMN1; SMN2MEN1RAB9A
SCHEMBL28598128 0.83 TP53 (0.48) TSHRMEN1KMT2ATHRBPLA2G4B
SCHEMBL27771467 0.83 GABRP (0.40) HSD17B10TSHRSMN1; SMN2MEN1RAB9A
Hydrochloric Acid SCHEMBL2200718 0.81 TSHR (0.47) HSD17B10TSHRSMN1; SMN2MEN1RAB9A
SCHEMBL25396348 0.78 HSD17B10 (0.39) HSD17B10TSHRSMN1; SMN2MEN1RAB9A
SCHEMBL2540541 0.78 KDM4E (0.47) HSD17B10TSHRMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2847784-B1 POLISHING PAD WITH LIGHT-STABLE LIGHT-TRANSMITTING REGION CABOT MICROELECTRONICS CORP (US) 2017-07-05 EP claimed
US-9156125-B2 Polishing pad with light-stable light-transmitting region CABOT MICROELECTRONICS CORPORATION (US) 2015-10-13 US claimed
US-20130273813-A1 POLISHING PAD WITH LIGHT-STABLE LIGHT-TRANSMITTING REGION CABOT MICROELECTRONICS CORPORATION (US) 2013-10-17 US claimed
EP-2705550-B1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2017-07-05 EP disclosed
EP-2847784-B1 POLISHING PAD WITH LIGHT-STABLE LIGHT-TRANSMITTING REGION CABOT MICROELECTRONICS CORP (US) 2017-07-05 EP disclosed
US-9156125-B2 Polishing pad with light-stable light-transmitting region CABOT MICROELECTRONICS CORPORATION (US) 2015-10-13 US disclosed
US-20130273813-A1 POLISHING PAD WITH LIGHT-STABLE LIGHT-TRANSMITTING REGION CABOT MICROELECTRONICS CORPORATION (US) 2013-10-17 US disclosed