⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15312468 | 1.00 | — | — | |
| SCHEMBL2616623 | 0.83 | — | — | |
| SCHEMBL3888280 | 0.83 | — | — | |
| SCHEMBL8719302 | 0.83 | — | — | |
| SCHEMBL2808877 | 0.81 | — | — | |
| SCHEMBL2808880 | 0.81 | — | — | |
| SCHEMBL2811491 | 0.77 | ALDH1A1 (0.36) | — | |
| SCHEMBL8842470 | 0.77 | TSHR (0.41) | — | |
| SCHEMBL8842466 | 0.77 | TSHR (0.41) | — | |
| SCHEMBL7765784 | 0.77 | HCAR2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9174972-B2 | Cognition enhancing compounds and compositions, methods of making, and methods of treating | NEUROSOLIS, INC. (US) | 2015-11-03 | — | — | US | disclosed |
| US-20130274299-A1 | Cognition Enhancing Compounds and Compositions, Methods of Making, and Methods of Treating | MAPLIGHT THERAPEUTICS, INC. | 2013-10-17 | — | — | US | disclosed |