Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115853 | 0.92 | XIAP (0.41) | ALDH1A1XIAPCTSB | |
| SCHEMBL2115900 | 0.88 | ALDH1A1 (0.37) | SMN1; SMN2LMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15095357 | 0.84 | XIAP (0.42) | SMN1; SMN2MEN1KMT2AXIAPPOLB | |
| SCHEMBL2114000 | 0.84 | XIAP (0.38) | L3MBTL1MAPTXIAP | |
| SCHEMBL2115163 | 0.81 | XIAP (0.42) | CYP3A4CYP2C9CYP2C19GAAMAPT | |
| SCHEMBL2113164 | 0.81 | XIAP (0.43) | SMN1; SMN2CYP2C9GAAALDH1A1XIAP | |
| SCHEMBL2115282 | 0.80 | XIAP (0.40) | ALDH1A1XIAP | |
| SCHEMBL2114216 | 0.79 | EPHX2 (0.40) | SMN1; SMN2CYP3A4CYP2C9CYP2C19TP53 | |
| SCHEMBL2115895 | 0.79 | XIAP (0.45) | CYP3A4CYP2C9CYP2C19XIAP | |
| SCHEMBL2113658 | 0.78 | XIAP (0.35) | CYP3A4CYP2C9CYP2C19XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130274278-A1 | IAP INHIBITORS | TETRALOGIC PHARM CORP (US) | 2013-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274278-A1 | IAP INHIBITORS | XIAP, IAPP, BIRC5 | SMN1; SMN2 1032/4885LMNA 767/4885CYP3A4 3818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.