Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1531145 | 0.89 | LMNA (0.47) | LMNAKMT2ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL1531185 | 0.89 | LMNA (0.48) | LMNAKMT2ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL1531121 | 0.86 | LMNA (0.48) | LMNAKMT2ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL13303557 | 0.79 | KMT2A (0.50) | LMNAKMT2ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL1562510 | 0.78 | KMT2A (0.47) | LMNAKMT2ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL1531195 | 0.78 | LMNA (0.48) | LMNAKMT2ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL1531088 | 0.78 | SMN1; SMN2 (0.49) | LMNAKMT2ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL1531178 | 0.78 | LMNA (0.48) | LMNAKMT2ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL1531174 | 0.77 | LMNA (0.47) | LMNAKMT2ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL1531167 | 0.77 | LMNA (0.47) | LMNAKMT2ASMN1; SMN2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292606-A1 | Pyrazole derivative, its intermediate, and herbicide containing the same as active ingredient | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2011-03-09 | — | — | EP | disclosed |
| US-20100152443-A1 | PYRAZOLE DERIVATIVE, INTERMEDIATE THEREFOR, PROCESSES FOR PRODUCING THESE, AND HERBICIDE CONTAINING THESE AS ACTIVE INGREDIENT | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2010-06-17 | — | — | US | disclosed |
| US-7700786-B2 | Pyrazole derivative, intermediate therefor, processes for producing these, and herbicide containing these as active ingredient | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2010-04-20 | — | — | US | disclosed |
| US-20050070441-A1 | Pyrazole derivative, intermediate therefor, processes for producing these, and herbicide containing these as active ingredient | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2005-03-31 | — | — | US | disclosed |
| EP-1362852-A1 | PYRAZOLE DERIVATIVE, INTERMEDIATE THEREFOR, PROCESSES FOR PRODUCING THESE, AND HERBICIDE CONTAINING THESE AS ACTIVE INGREDIENT | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152443-A1 | PYRAZOLE DERIVATIVE, INTERMEDIATE THEREFOR, PROCESSES FOR PRODUCING THESE, AND HERBICIDE CONTAINING THESE AS ACTIVE INGREDIENT | CYP51A1, CYP4F11, WEE1 | LMNA 4711/4885KMT2A 2709/4885SMN1; SMN2 4843/4885 |
| US-20050070441-A1 | Pyrazole derivative, intermediate therefor, processes for producing these, and herbicide containing these as active ingredient | CYP51A1, CYP4F11, WEE1 | LMNA 4711/4885KMT2A 2709/4885SMN1; SMN2 4843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.