SCHEMBL1531365

SCHEMBL1531365

CCCCCCCCCCCCCCCCCCOP1Oc2c(cc(C(C)(C)C)cc2C(C)(C)C)Cc2cc(C(C)(C)C)cc(C(C)(C)C)c2O1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 3/20 0.35
CD14 P08571 3/20 0.35
LY96 Q9Y6Y9 3/20 0.35
PTGS2 P35354 2/20 0.32
ELANE P08246 1/20 0.32
CD69 Q07108 1/20 0.32
THRA P10827 1/20 0.31
THRB P10828 1/20 0.31
ALOX5 P09917 1/20 0.31
PTGS1 P23219 1/20 0.31
NR5A2 O00482 1/20 0.30
NR5A1 Q13285 1/20 0.30
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30
RXRG P48443 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14533611 1.00 TLR4 (0.35) TLR4CD14LY96PTGS2ELANE
SCHEMBL6435626 1.00 TLR4 (0.35) TLR4CD14LY96PTGS2ELANE
SCHEMBL5048789 1.00 TLR4 (0.35) TLR4CD14LY96PTGS2ELANE
SCHEMBL5051084 1.00 TLR4 (0.35) TLR4CD14LY96PTGS2ELANE
SCHEMBL6431828 1.00 TLR4 (0.35) TLR4CD14LY96PTGS2ELANE
SCHEMBL98164 1.00 TLR4 (0.35) TLR4CD14LY96PTGS2ELANE
SCHEMBL14534435 0.95 TLR4 (0.33) TLR4CD14LY96PTGS2
SCHEMBL31335157 0.93 TLR4 (0.30) TLR4CD14LY96PTGS2NR5A2
SCHEMBL17636611 0.92 TLR4 (0.31) TLR4CD14LY96
SCHEMBL5048780 0.90 ELANE (0.34) TLR4CD14LY96ELANECD69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3299401-B1 ACRYLIC BLOCK COPOLYMER, RESIN COMPOSITION AND MOLDED BODY COMPRISING SAME, AND OPTICAL MEMBER KURARAY CO (JP) 2021-03-10 EP disclosed
US-10935697-B2 Resin composition including acrylic block copolymer and light diffusing agent KURARAY CO., LTD. (JP) 2021-03-02 US disclosed
US-20200057176-A1 RESIN COMPOSITION INCLUDING ACRYLIC BLOCK COPOLYMER AND LIGHT DIFFUSING AGENT KURARAY CO., LTD. (JP) 2020-02-20 US disclosed
US-10563001-B2 Acrylic block copolymer, resin composition and shaped article including the same, and optical component KURARAY CO., LTD. (JP) 2020-02-18 US disclosed
US-20180112023-A1 ACRYLIC BLOCK COPOLYMER, RESIN COMPOSITION AND SHAPED ARTICLE INCLUDING THE SAME, AND OPTICAL COMPONENT KURARAY CO., LTD. (JP) 2018-04-26 US disclosed
EP-3299401-A1 ACRYLIC BLOCK COPOLYMER, RESIN COMPOSITION AND MOLDED BODY COMPRISING SAME, AND OPTICAL MEMBER Kuraray Co., Ltd. (JP) 2018-03-28 EP disclosed
EP-2683011-B1 NONAQUEOUS ELECTROLYTE SOLUTION FOR BATTERIES, AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY USING SAME DENSO CORP (JP) 2018-02-28 EP disclosed
EP-1795560-B1 POLYLACTIC ACID RESIN COMPOSITION, MOLDINGS, AND PROCESS FOR PRODUCTION THEREOF ADEKA CORP (JP) 2013-05-22 EP disclosed
US-8287778-B2 Ultraviolet absorber composition with improved heat resistance and synthetic resin composition containing the same ADEKA CORPORATION (JP) 2012-10-16 US disclosed
US-20110272648-A1 ULTRAVIOLET ABSORBER COMPOSITION WITH IMPROVED HEAT RESISTANCE AND SYNTHETIC RESIN COMPOSITION CONTAINING THE SAME ADEKA CORPORATION (JP) 2011-11-10 US disclosed
EP-1359195-A1 AROMATIC-ALIPHATIC COPOLYCARBONATE RESIN COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2003-11-05 EP disclosed
EP-0622404-B1 Crystalline synthetic resin composition containing a group III or IV metal salt of a cyclic organophosphoric ester ASAHI DENKA KOGYO KK (JP) 1998-07-08 EP disclosed
EP-0359276-B1 Stabilized synthetic resin composition ASAHI DENKA KOGYO KK (JP) 1995-08-30 EP disclosed
EP-0622404-A1 Crystalline synthetic resin composition containing a group III or IV metal salt of a cyclic organophosphoric ester ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1994-11-02 EP disclosed
US-5342868-A Containing alkali metal salt and polyvalent metal salt of a cyclic organophosphoric ester ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1994-08-30 US disclosed
US-5238979-A Bisphenol phosphites and a phenol ASAHI DENKA KOGYO K.K. (JP) 1993-08-24 US disclosed
US-5055507-A Bisphenol phosphite/phenol mixture for enhancing heat and radiation resistance ASAHI DENKA KOGYO K.K. (JP) 1991-10-08 US disclosed
US-5039723-A Mixture of cyclic phosphite and hindered amine ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1991-08-13 US disclosed
EP-0395030-A1 Polyolefin resins containing ziegler type complex catalyst residues stabilized with organic phosphites ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1990-10-31 EP disclosed
EP-0359276-A2 Stabilized synthetic resin composition ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1990-03-21 EP disclosed