Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 3/20 | 0.35 |
| ▸ | CD14 | P08571 | 3/20 | 0.35 |
| ▸ | LY96 | Q9Y6Y9 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CD69 | Q07108 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.30 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14533611 | 1.00 | TLR4 (0.35) | TLR4CD14LY96PTGS2ELANE | |
| SCHEMBL5048789 | 1.00 | TLR4 (0.35) | TLR4CD14LY96PTGS2ELANE | |
| SCHEMBL5051084 | 1.00 | TLR4 (0.35) | TLR4CD14LY96PTGS2ELANE | |
| SCHEMBL6431828 | 1.00 | TLR4 (0.35) | TLR4CD14LY96PTGS2ELANE | |
| SCHEMBL98164 | 1.00 | TLR4 (0.35) | TLR4CD14LY96PTGS2ELANE | |
| SCHEMBL1531365 | 1.00 | TLR4 (0.35) | TLR4CD14LY96PTGS2ELANE | |
| SCHEMBL14534435 | 0.95 | TLR4 (0.33) | TLR4CD14LY96PTGS2 | |
| SCHEMBL31335157 | 0.93 | TLR4 (0.30) | TLR4CD14LY96PTGS2NR5A2 | |
| SCHEMBL17636611 | 0.92 | TLR4 (0.31) | TLR4CD14LY96 | |
| SCHEMBL5048780 | 0.90 | ELANE (0.34) | TLR4CD14LY96ELANECD69 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1283245-B1 | POLYESTER RESIN COMPOSITION AND PROCESS FOR THE PREPARATION THEREOF | KANEKA CORP (JP) | 2005-11-09 | — | — | EP | disclosed |
| US-20040024139-A1 | Polyester resin composition and process for the preparation thereof | KANEKA CORPORATION (JP) | 2004-02-05 | — | — | US | disclosed |
| EP-1283245-A1 | POLYESTER RESIN COMPOSITION AND PROCESS FOR THE PREPARATION THEREOF | KANEKA CORPORATION (JP) | 2003-02-12 | — | — | EP | disclosed |