Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15291459 | 1.00 | TSHR (0.37) | TSHR | |
| SCHEMBL8676575 | 0.71 | MAPT (0.48) | TSHR | |
| SCHEMBL8912413 | 0.71 | ALOX15 (0.39) | TSHR | |
| SCHEMBL8912423 | 0.71 | ALOX15 (0.39) | TSHR | |
| SCHEMBL18138232 | 0.71 | ALOX15 (0.39) | TSHR | |
| SCHEMBL24245771 | 0.71 | ALOX15 (0.39) | TSHR | |
| SCHEMBL24245773 | 0.71 | ALOX15 (0.39) | TSHR | |
| SCHEMBL3503734 | 0.71 | ALOX15 (0.39) | TSHR | |
| SCHEMBL13140151 | 0.64 | TSHR (0.35) | TSHR | |
| SCHEMBL7752634 | 0.60 | CYP3A4 (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2851415-B1 | Novel quinazoline derivatives and their use in perfume compositions | INT FLAVORS & FRAGRANCES INC (US) | 2016-04-27 | — | — | EP | disclosed |
| EP-2851415-A1 | Novel quinazoline derivatives and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2015-03-25 | — | — | EP | disclosed |
| US-8557876-B2 | Pyrimidine derivatives and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2013-10-15 | — | — | US | disclosed |