Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC5A1 | P13866 | 5/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 4/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27856156 | 1.00 | NPC1 (0.41) | NPC1RAB9ASLC5A1SLC5A2MGAM | |
| SCHEMBL153143 | 1.00 | NPC1 (0.41) | NPC1RAB9ASLC5A1SLC5A2MGAM | |
| SCHEMBL153142 | 0.91 | SLC5A2 (0.34) | NPC1RAB9ASLC5A1SLC5A2APP | |
| SCHEMBL27856157 | 0.89 | NPC1 (0.42) | NPC1RAB9ASLC5A1SLC5A2MGAM | |
| SCHEMBL157543 | 0.89 | NPC1 (0.42) | NPC1RAB9ASLC5A1SLC5A2MGAM | |
| SCHEMBL157544 | 0.89 | NPC1 (0.42) | NPC1RAB9ASLC5A1SLC5A2MGAM | |
| SCHEMBL154136 | 0.86 | APP (0.41) | SLC5A1SLC5A2TYRAPPSNCA | |
| SCHEMBL155667 | 0.86 | SLC5A2 (0.40) | SLC5A1SLC5A2 | |
| SCHEMBL28795196 | 0.86 | APP (0.41) | SLC5A1SLC5A2TYRAPPSNCA | |
| SCHEMBL154137 | 0.86 | APP (0.41) | SLC5A1SLC5A2TYRAPPSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| US-20120058503-A1 | Novel Indicator Platform | BIOSYNTH AG (CH) | 2012-03-08 | — | — | US | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |