Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.40 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.40 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28795196 | 1.00 | APP (0.41) | APPSNCASLC5A1SLC5A2SLC28A3 | |
| SCHEMBL154136 | 1.00 | APP (0.41) | APPSNCASLC5A1SLC5A2SLC28A3 | |
| SCHEMBL155035 | 0.92 | SLC28A3 (0.45) | SNCASLC5A1SLC5A2SLC28A3TYR | |
| SCHEMBL155034 | 0.92 | SLC28A3 (0.45) | SNCASLC5A1SLC5A2SLC28A3TYR | |
| SCHEMBL154135 | 0.90 | TP53 (0.35) | APPSLC5A2POLBLDHA | |
| SCHEMBL155667 | 0.88 | SLC5A2 (0.40) | SLC5A1SLC5A2SLC28A3ATM | |
| SCHEMBL27856153 | 0.88 | SLC5A2 (0.40) | SLC5A1SLC5A2SLC28A3ATM | |
| SCHEMBL155668 | 0.88 | SLC5A2 (0.40) | SLC5A1SLC5A2SLC28A3ATM | |
| SCHEMBL153143 | 0.86 | NPC1 (0.41) | APPSNCASLC5A1SLC5A2TYR | |
| SCHEMBL27856156 | 0.86 | NPC1 (0.41) | APPSNCASLC5A1SLC5A2TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| US-20120058503-A1 | Novel Indicator Platform | BIOSYNTH AG (CH) | 2012-03-08 | — | — | US | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |