Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 3/20 | 0.31 |
| ▸ | SCD | O00767 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL972272 | 0.86 | AOC3 (0.49) | PLA2G7NPC1AOC3RAB9A | |
| SCHEMBL12919431 | 0.85 | SMN1; SMN2 (0.39) | PLA2G7ALDH1A1POLBNPC1RAB9A | |
| SCHEMBL16556640 | 0.82 | NOS1 (0.40) | PLA2G7ALDH1A1NPC1AOC3RAB9A | |
| SCHEMBL974419 | 0.76 | AOC3 (0.57) | AOC3 | |
| SCHEMBL16266054 | 0.74 | AOC3 (0.46) | ALDH1A1NPC1AOC3RAB9AHTT | |
| SCHEMBL16271071 | 0.72 | AOC3 (0.49) | ALDH1A1POLBNPC1AOC3RAB9A | |
| SCHEMBL973232 | 0.72 | AOC3 (0.47) | AOC3 | |
| SCHEMBL15177672 | 0.72 | AOC3 (0.44) | NPC1AOC3RAB9A | |
| SCHEMBL16266051 | 0.72 | AOC3 (0.47) | NPC1AOC3RAB9A | |
| SCHEMBL12919507 | 0.72 | SMN1; SMN2 (0.36) | ALDH1A1POLBNPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2650287-A1 | Thiazole Derivative and use thereof as VAP-1 Inhibitor | R-Tech Ueno, Ltd. (JP) | 2013-10-16 | — | — | EP | disclosed |